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Wilde-Lee
News Synthesis | 26 Aug 2014

Deep Brain Stimulation Helpful in Some Patients With MS Tremor

There are few treatment options for patients with MS-related tremor. For some, a radical surgery called deep brain stimulation helps immensely.

Cynthia McKelvey
Shortly after she was diagnosed with relapsing-remitting multiple sclerosis in 2001, Angela Wilde-Lee’s right arm developed...
Clinical Research, People
DNA methylation
News Synthesis | 29 Jul 2014

Epigenetics in MS: A Primer

Epigenetic changes may account for much of the heterogeneity in MS, both in disease onset and progression

Cynthia McKelvey
The most vexing and enduring question in multiple sclerosis research may be: Why do some people...
Laboratory Research
Microglia Figure 4
News Synthesis | 3 Jul 2014

Microglia, Molecularly Defined

Microglia—the innate immune cells of the brain and spinal cord—have long been blamed for stoking MS lesions, but more recent studies suggest they may also have the power to protect tissue and promote repair

Carol Cruzan Morton
In multiple sclerosis, circulating immune cells get plenty of well-deserved bad press for...
Laboratory Research
Magnetic transfer ratio
News Synthesis | 29 May 2014

Tracking Remyelination: Do You See What I See?

Several new imaging modalities are aimed at evaluating possible remyelination in patients with multiple sclerosis. This article discusses how the techniques work and their potential applications to MS, as well as their limitations.

Steven Fox
For nearly 15 years, magnetic resonance imaging has been an important tool for...
Clinical Research
month of birth
News Synthesis | 24 Apr 2014

Is the Month-of-Birth Effect on MS Risk a Statistical Fluke?

Since the late 1980s, a series of papers have reported that people born in late spring, especially in May, are at greater risk for MS. Two recent papers contend that these results are a statistical fluke.

Jennie Dusheck, M.A.
Scores of papers published in the last quarter-century have reported that people with MS are more likely to...
Methods, People
Orion wanted poster
News Synthesis | 22 Apr 2014

Decoding Brain Disease

Computer analyses extract new insights from MS patient data

Carol Cruzan Morton
Since he was diagnosed with multiple sclerosis in 2007, Curtis Schreiner, a three-time U.S. Olympian in the biathlon, has...
Clinical Research, Drug Development, Laboratory Research, Meetings, Methods, People
clothed cows
News Synthesis | 19 Mar 2014

Beyond Reasonable Doubt: The vitamin D piece of the MS puzzle

Clothed cows—and cows wearing only bras—are proving critical in understanding how the body acquires and handles vitamin D and unraveling the vitamin’s role in the development of MS

Jennie Dusheck
Last summer, MSDF reported a dramatic study demonstrating that vitamin D supplementation could...
Laboratory Research
NMO Fig 1
News Synthesis | 22 Oct 2013

Neuromyelitis Optica, Part 4: Unresolved Questions

And finally, a look at some unresolved questions, such as people diagnosed with NMO who don’t have the aquaporin antibody, and the funding situation

Andreas von Bubnoff
A recent study that compared several antibody assays found that about a quarter of patients diagnosed with NMO lack...
Clinical Research, Drug Development, Laboratory Research, People
NMO Fig 1
News Synthesis | 22 Oct 2013

Neuromyelitis Optica, Part 3: Treatment and Prevention

After discussing NMO pathogenesis, we’ll talk about current treatments, as well as efforts to find better treatments and even prevent NMO attacks

Andreas von Bubnoff
Because NMO patients essentially suffer from inflammation, doctors first try to stop an acute NMO attack with...
Clinical Research, Drug Development, Laboratory Research, People

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