Old Drug Performs New Trick
The Secrets of Shapeshifting Cells
Lessons From Fingolimod for PPMS
Papers of the Week
Welcome to the Multiple Sclerosis Discovery Forum
Researchers are in the early stages of experimenting with electrical stimulation techniques to improve cognition in multiple sclerosis and other brain disorders. Don't try this at home, they caution.
Studies in animals and people have linked obesity to inflammatory diseases, such as multiple sclerosis. Researchers at Johns Hopkins University are testing calorie restriction for its safety and effectiveness in reducing disease severity in people with relapsing-remitting MS.
Some people with MS have small long-lasting inflammatory lesions in the lining outside the brain, which may play a role in progressive disease. The discovery has prompted researchers to try to target these lesions more directly.
To preserve brain health in multiple sclerosis, research suggests the optimal treatment regime starts early and closely monitors patients by MRI if possible to switch therapies before a disabling relapse.
What happens to the course of multiple sclerosis when people stop taking their drugs? It depends on the individual and on the drug. A new study may help answer the question better.
In what may be the first demonstration of myelin repair in people with multiple sclerosis, an old antihistamine shows modest improvement in the function of chronically demyelinated optic nerves.
Tools that will help investigators conceive and perform experimental work:
The Data Visualization section presents MS-related data in new ways, making it easy for viewers to discover unexpected relationships
Our latest data visualization presents a network map of the connections among 1253 authors of 263 research papers that reported results of clinical trials in progressive forms of multiple sclerosis between January 1983 and September 2015.
- Drug-Development Pipeline consolidates key information about compounds under investigation for therapeutic use
- Tissue Repositories lists features of the world's tissue repositories and brain banks, including rules of engagement and contact information
- Clinical Trials lists sources of information about MS clinical trials
Drug Database Updates:
The drug database, updated weekly from 5/14/2012 to 4/20/2016, contains detailed information about 44 approved and experimental drugs to treat multiple sclerosis, including clinical trials, regulatory actions, mechanisms of action, and side effects. Updates have been suspended due to lack of funding
Meetings and Events catalogs future and past meetings of interest to the MS-research community
- Funding Opportunities provides information about where to obtain grants
- Jobs offers descriptions of available positions
Member Directory displays profiles of MS-research community members
Bulletin Board allows MSDF members to post notices
Useful Links lists helpful resources elsewhere on the web
I’ve been browsing various MS forums since my girlfriend started taking Copaxone for h
To whom it may concern,