Novel Remyelination AssayOligodendrocytes wrap around glass micropillars, allowing high-throughput assays of potential remyelination agents.
Rare Family MS Cluster Reveals New Clues
The Natural History of MS Symptoms
Myelin and Axons Don’t Form a Uniform Union
Stem Cells Stop the Train of MS Damage in Mice
Welcome to the Multiple Sclerosis Discovery Forum
A new global brain MRI study shows that patients who test positive for oligoclonal bands have greater loss of white matter than MS patients lacking those bands. The results of the study suggest that there may be reason to consider MS patients without oligoclonal bands to be a clinically distinct subgroup.
The recent availability of a variety of disease-modifying therapies for RRMS raises many questions about when and which DMTs patients should start or stop before and during pregnancy
A study demonstrates that an iPad app can accurately gauge walking, balance, manual dexterity, visual acuity, and a measure of cognition in people with MS
Tools that will help investigators conceive and perform experimental work:
The Data Visualization section presents MS-related data in new ways, making it easy for viewers to discover unexpected relationships
Our latest visualization is based on the study Natural History of Multiple Sclerosis Symptoms, which appeared in the Fall 2013 issue of the International Journal of MS Care. It shows how the symptoms of multiple sclerosis change over the course of a lifetime. As we explained in the article we published in November 2013, Ilya Kister, M.D., of the NYU Multiple Sclerosis Care Center, Department of Neurology, NYU School of Medicine, New York, NY, and colleagues used data from 25,728 patients in the NARCOMS Registry to develop a series of symptom severity charts in 11 domains commonly affected in MS.
- Drug-Development Pipeline consolidates key information about compounds under investigation for therapeutic use
We've added three new trials, updated information on two trials, and added 16 other pieces of information. The drugs with important additions and changes are dimethyl fumarate, fingolimod, glatiramer acetate, interferon β-1a, interferon β-1b, minocycline, and natalizumab.
- Tissue Repositories lists features of the world's tissue repositories and brain banks, including rules of engagement and contact information
- MSGene provides a comprehensive, unbiased and regularly updated collection of genetic association studies performed on multiple sclerosis phenotypes
- Clinical Trials lists sources of information about MS clinical trials
Meetings and Events catalogs future and past meetings of interest to the MS-research community
- Funding Opportunities provides information about where to obtain grants
- Jobs offers descriptions of available positions
Member Directory displays profiles of MS-research community members
Bulletin Board allows MSDF members to post notices
Useful Links lists helpful resources elsewhere on the web
Most Popular Content
- Novel Remyelination Assay Allows High-Throughput Drug Screening
- More Than Meets the Eye
- Who We Are
- Harnessing Epitope Spreading to Treat MS
- Explaining Fingolimod’s Fatal Flaw
- Low Testosterone Linked to Disability in Men With MS
- Small Internal Jugular Veins Linked to Severe MS
- Beyond Reasonable Doubt: The vitamin D piece of the MS puzzle
- Old Drug May Wield New Power
- MS Research Roundup: March 31, 2014
- Make Way for Another MS Model?
- Phase 1 Trial of Stem Cells Begins in MS
- The Many Faces of B Cells
- Genomic Double Play
- Clinical Trials in Multiple Sclerosis
- More Signal Abnormalities Seen in Relatives of MS Patients
- New MS Clinical Course Descriptions Reflect Disease Activity
- Myelin and Axons Don’t Form a Perfect, Uniform Union
- Sniffing Out Demyelination
- New Pathogen Linked to MS
- Rare Family Cluster of MS Reveals New Clues
- Stem Cells Enhanced to Generate Myelin-Producing Cells
- Single Calcitriol Dose Beats Back EAE in Mice
- MS Cognitive Impairment Rates Lower Than Previously Reported
- Early B Cells Found in Gut, Schooled by Microbes
- Corticosteroids Ineffective for Many With Relapsing MS
- Serum Vitamin D Levels Predict Severity of MS
- Switches to Fingolimod, Natalizumab Show Similar Efficacy
- Vitamin D3 Blocks T Helper Cells From Entering the CNS
- Is Normal Pressure Hydrocephalus A Component of Multiple Sclerosis Pathology?
- Remyelination: Are Exosomes Containing microRNA the Answer?
- First-Attack Multiple Sclerosis Targets Gray Matter
- Easy Cognitive Assessments for People With MS
- MS Research Roundup: April 8, 2014
- Venocentric Lesions on MRI: An Early Marker of MS?
- MS Research Roundup: March 21, 2014
- Decoding Brain Disease
- Genetic Associations
- Pregnancy’s Secret Weapon?
- Scientific Literature TreeMap
- Type 1 Diabetes Linked to Higher MS Risk Among Youth
- MS Patient, Ph.D.
- Can Gut Microbes Provide Answers About MS?
- PPMS vs. RRMS: A Distinction Without a Difference?
- A Complementary Approach to Treating MS?
- Plasma Osteopontin Levels: A New Marker for MS?
- Sleep Boosts Remyelinating Glial Cells
- MS Research Roundup: April 30, 2014
- Anti-Inflammatory Apolipoprotein May Protect Against MS Symptoms
- MS Research Roundup: February 12, 2014
- MS Research Roundup: February 26, 2014
- The Oligodendrocyte Whisperer
- Gut Bacteria Boost Anti-Inflammatory Immune Cells in Mice
- FDA's Denial of Alemtuzumab Stirs Controversy
- Transdermal Myelin Peptides May Be Safe, Effective in MS
- Survey Finds “MSer” to Be Patients' Preferred Descriptor
- Cheap Vaccine Slows MS Progression
- MS Research Roundup: May 27, 2014
- Cortical MS Lesions Linked to “Normal” White Matter Injury
- Early-Detection Probe for MS Exploits Coagulation Protein
- Abnormal Venous Outflow Dynamics May Not Be Implicated in MS
- Anti-EBV Serology, HLA-DR Risk Profiles May Help Identify MS
- PUMA Protein May Underlie Oligodendroglial Cell Death in MS
- Toso: A New Drug Target for MS?
- Blood Serum From Relapsing MS Patients May Damage the Blood-Brain Barrier
- Tears Yield Possible MS Biomarker
- MS Family Planning 101: Should DMTs Be Discontinued Before and During Pregnancy?
- Multiple Sclerosis Discovery Podcast
- Autologous Stem Cell Transplant Effective in Inflammatory RRMS; Mechanism Emerging
- New MS Drug Candidate From Zebrafish Screen Targets IGF-1R Pathway
- EDSS Alternative in an iPad
- MS Patient, Ph.D.: MS and Vitamin D: What’s a Patient to Do?
- Signaling Pathway Important in Colon Cancer Implicated in Maturational Arrest of OPCs
- High Noon at the Th17 Corral
- Genetic Marker May Underlie Sex Difference in MS Susceptibility
- Comorbidities, Both Physical and Mental, Are Pervasive in MS
- Cannabinoid Receptor Variant Linked to MS Neurodegeneration
- MS Research Roundup: January 15, 2014
- MS Patient, Ph.D.: Greetings From Limbo Land
- CCSVI Not Linked to MS in Large Study
- Sex Differences in MS Are Genetic, Not Just Hormonal
- MS Patient, Ph.D.: Axes of Access Don’t Intersect for the Disabled Patient
- National MS Society Partners With Accelerated Cure Project Online Forum to Drive Progress
- A New MS Journal
- Kir4.1 Potassium Channels in MS: Discrepant Results From Two Studies
- Antigen-Specific Therapy for MS Passes Safety Test
- New NARCOMS Analysis Focuses on Symptom-Specific Impairment
- Microglia, Molecularly Defined
- Please log in or email us
- How should we refer to someone with MS?
- Optical Coherence Tomography: New Evidence Lends Support for MS Diagnosis
- A Better Interferon?
- Benign MS Expresses Itself
- MS-SMART Trial for Secondary Progressive MS Announced
- Natalizumab Emerges on Top in Network Meta-Analysis
- Video Game Revs Up Brain Power
- Sexual Dysfunction Fuels Mental Problems in MS Patients
- Oral Laquinimod May Reduce Destructive Pathology in RRMS
- MS Research Roundup: June 19, 2014
- B Cells Step Into the Limelight
- MS and South hemisphere