Clinical Research

Peripheral B Cell Activation May Drive CNS Autoimmunity in MS

Two studies show that memory B cells actively traffic between peripheral lymphoid tissue and the CNS, thereby shedding light on the mechanisms of some current MS therapies and suggesting future avenues for therapeutic development

Pathological B lymphocytes are most likely activated in the periphery in patients with multiple sclerosis and then...

Clinical Research

MS Research Roundup: August 13, 2014

Social Media and Clinical Trials; Scientists on Social Media; Talking Simply About Science; Reaching Out With Reddit

Items of interest to multiple sclerosis researchers from around the Web...

Clinical Research, People

Interferon β and Glatiramer Acetate Are Clinically Similar, Says Cochrane Meta-Analysis

A review of five head-to-head clinical trials suggests that interferon β and glatiramer acetate are clinically similar disease-modifying therapies with some differences in MRI outcomes that clinicians should consider

A recent review from the Cochrane Collaboration looked at the efficacy of interferons β and glatiramer acetate for...

Clinical Research

Lower Risk of MS in People With HIV

A large study of hospital records in England finds a potentially protective association now being tested in a small clinical trial

A controversial idea about how ancient inherited viruses embedded in people’s genes may cause...

Clinical Research, Drug Development

MRI Detects Early MS-Like Changes in Rare Eye Disease

The association between a rare mitochondrial eye disease and MS grows curiouser and curiouser. Do the two conditions occur together by chance, or is there more to it than meets the eye?

Some patients with the rare mitochondrial eye disease Leber hereditary optic neuropathy develop...

Clinical Research

MS Patient, Ph.D.: Calling Dr. Thomas Hale

One researcher’s idea for a symbiotic relationship between (pregnant and breast-feeding) patients and evidence-based medicine

Since the birth of my daughter, the question of when to restart...

Clinical Research, People

Physical Activity Associated With Improved Quality of Life in People With MS

An international survey of over 2000 people with MS shows that moderate to high levels of physical activity are associated with better health-related quality of life

Physical activity is highly associated with better quality of life in people with MS, according to...

Clinical Research

Evaluating Patient Preferences Is Key for MS Decision-Making

Taking patient preferences into account may significantly affect patients’ initial and long-term compliance with therapy

Evaluating patient preferences is a crucial step in shared decision-making in relapsing–remitting multiple sclerosis, and it’s...

Clinical Research, People

MS Research Roundup: July 28, 2014

Stem Cell Clinical Trial; Black Mouse Wake-Up Call; Vitamin D Associated With More Severe Acute Optic Neuritis; Nanotechnology Research Project

Items of interest to multiple sclerosis researchers from around the Web...

Clinical Research, Laboratory Research

MS Patients Positive for Oligoclonal Bands Have Greater Brain Atrophy

A new global brain MRI study shows that patients who test positive for oligoclonal bands have greater loss of white matter than MS patients lacking those bands. The results of the study suggest that there may be reason to consider MS patients without oligoclonal bands to be a clinically distinct subgroup.

Patients lacking oligoclonal bands have less overall brain atrophy than those who...

Clinical Research

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Peripheral B Cell Activation May Drive CNS Autoimmunity in MS

MS Research Roundup: August 13, 2014

Interferon β and Glatiramer Acetate Are Clinically Similar, Says Cochrane Meta-Analysis

Lower Risk of MS in People With HIV

MRI Detects Early MS-Like Changes in Rare Eye Disease

MS Patient, Ph.D.: Calling Dr. Thomas Hale

Physical Activity Associated With Improved Quality of Life in People With MS

Evaluating Patient Preferences Is Key for MS Decision-Making

MS Research Roundup: July 28, 2014

MS Patients Positive for Oligoclonal Bands Have Greater Brain Atrophy

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Clinical Research

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