Clinical Research

MS Discovery Forum to Suspend Publication

Lack of funding ends new content, but archive remains open and free.

We are announcing important changes at MS Discovery Forum. After July, MSDF will suspend new content creation and publishing activities.

Clinical Research, Drug Development, Laboratory Research, Meetings, Methods, People

Episode 88 with Dr. John Hart on electrical stimulation for cognition in MS

Researchers are in the early stages of experimenting with electrical stimulation techniques to improve cognition in multiple sclerosis and other brain disorders. Don't try this at home, they caution.

Clinical Research, Drug Development

Episode 87 with Dr. Ellen Mowry on testing restricted calorie diets in MS

Studies in animals and people have linked obesity to inflammatory diseases, such as multiple sclerosis. Researchers at Johns Hopkins University are testing calorie restriction for its safety and effectiveness in reducing disease severity in people with relapsing-remitting MS.

Clinical Research

Episode 86 with Dr. Pavan Bhargava on targeting lesions lining the brain

Some people with MS have small long-lasting inflammatory lesions in the lining outside the brain, which may play a role in progressive disease. The discovery has prompted researchers to try to target these lesions more directly.

Clinical Research, Drug Development

Episode 85 with Dr. Eva Havrdová on detecting a sub-optimal response to MS therapy

To preserve brain health in multiple sclerosis, research suggests the optimal treatment regime starts early and closely monitors patients by MRI if possible to switch therapies before a disabling relapse.

Clinical Research, Drug Development

Episode 84 with Dr. Ilya Kister on stopping MS drugs & observational datasets

What happens to the course of multiple sclerosis when people stop taking their drugs? It depends on the individual and on the drug. A new study may help answer the question better.

Clinical Research, Drug Development

Old Drug Performs New Trick

In what may be the first demonstration of myelin repair in people with multiple sclerosis, an old antihistamine shows modest improvement in the function of chronically demyelinated optic nerves.

Thanks in part to a close collaboration between a scientist and a physician, the prospect of...

Clinical Research, Drug Development, Laboratory Research, Meetings

Partnership and Consent in MS Decision-Making

Journal of the Neurological Sciences cover

With 10 disease-modifying therapies for MS, decision-making is becoming ever more complex, and clinicians should seek to form therapeutic partnerships with patients

The range of choices for managing multiple sclerosis is increasing, with 10 new therapies having...

Clinical Research

Episode 96 with Drs. Bibiana Bielekova and Mika Komori on a new CSF biomarker for MS

Analysis of cerebrospinal fluid from people with MS led to a surprising result, one which has intriguing implications for understanding and treating progressive MS.

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Clinical Research

Episode 94 with Dr. Oscar Fernandez on evaluating DMT risk in MS

Clinicians must carefully balance the risks and benefits of MS DMTs for each patient. Fortunately, there are tools, knowledge and research findings to help with this process. Dr. Fernandez describes the approaches he uses to perform this balancing act with his patients.

Clinical Research

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MS Discovery Forum to Suspend Publication

Episode 88 with Dr. John Hart on electrical stimulation for cognition in MS

Episode 87 with Dr. Ellen Mowry on testing restricted calorie diets in MS

Episode 86 with Dr. Pavan Bhargava on targeting lesions lining the brain

Episode 85 with Dr. Eva Havrdová on detecting a sub-optimal response to MS therapy

Episode 84 with Dr. Ilya Kister on stopping MS drugs & observational datasets

Old Drug Performs New Trick

Partnership and Consent in MS Decision-Making

Episode 96 with Drs. Bibiana Bielekova and Mika Komori on a new CSF biomarker for MS

Episode 94 with Dr. Oscar Fernandez on evaluating DMT risk in MS

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