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HERV
New Findings | 6 Aug 2014

Lower Risk of MS in People With HIV

A large study of hospital records in England finds a potentially protective association now being tested in a small clinical trial

Carol Cruzan Morton
A controversial idea about how ancient inherited viruses embedded in people’s genes may cause...
Clinical Research, Drug Development
Alice Tweedledum
New Findings | 5 Aug 2014

MRI Detects Early MS-Like Changes in Rare Eye Disease

The association between a rare mitochondrial eye disease and MS grows curiouser and curiouser. Do the two conditions occur together by chance, or is there more to it than meets the eye?

Ricki Lewis, Ph.D.
Some patients with the rare mitochondrial eye disease Leber hereditary optic neuropathy develop...
Clinical Research
The Multiple Sclerosis Performance Test
New Findings | 21 Jul 2014

EDSS Alternative in an iPad

A study demonstrates that an iPad app can accurately gauge walking, balance, manual dexterity, visual acuity, and a measure of cognition in people with MS

Mitch Leslie
Doctors, researchers, and patients could all benefit from an easier way to quantify...
Clinical Research, People
PoNS
New Findings | 14 Jul 2014

Portable Neuromodulation Device May Improve Walking in MS Patients

A recent study suggests that MS patients can improve walking performance using a device called the Portable Neuromodulation Stimulator. By stimulating the tongue, researchers believe they can facilitate neuroplasticity in the motor nuclei of the cerebellum.

Cynthia McKelvey
New research suggests that a device called the Portable Neuromodulation Stimulator may...
Clinical Research
Wnt pathway
New Findings | 9 Jul 2014

Signaling Pathway Important in Colon Cancer Implicated in Maturational Arrest of OPCs

New research draws a parallel between the pathological Wnt pathway of colon cancer and maturational arrest in oligodendrocyte progenitors. This surprising connection opens the door for a new way to look at white matter injury and MS.

Cynthia McKelvey
Undifferentiated oligodendrocyte progenitor cells can be found within many MS lesions. If only they could...
Laboratory Research
micropillar thumbnail
New Findings | 6 Jul 2014

Novel Remyelination Assay Allows High-Throughput Drug Screening

A new technology uses the actual myelin-making behavior of cells to look for drugs that may promote remyelination and prevent disability-causing nerve damage in people with MS. The first candidate is in clinical trials.

Carol Cruzan Morton
In the brains and spinal cords of people with multiple sclerosis, the repair of demyelinating lesions remains...
Clinical Research, Drug Development, Laboratory Research
fatigue mirror
New Findings | 2 Jul 2014

Damage to Strategic Brain Regions May Explain Fatigue in MS

Atrophy in the right anterior thalamic radiation, the right inferior temporal gyrus, and several other specific brain regions is linked to fatigue in persons with multiple sclerosis

Laurie Barclay, M.D.
Microstructural abnormalities and atrophy of white and gray matter in strategic brain regions are linked to...
Clinical Research
Peginterferon beta 1a
New Findings | 2 Jul 2014

A Better Interferon?

Subcutaneous injections of pegylated interferon β-1a once every 2 weeks may improve recovery from relapses and increase the likelihood of freedom from measurable disease activity

Lisa J. Bain
Pegylated interferon β-1a continues to show benefits similar to other currently available...
Clinical Research, Drug Development, Meetings
MACPF
New Findings | 24 Jun 2014

A Complementary Approach to Treating MS?

A new study bolsters the theory that the complement system drives persistent axon damage during remission. Anticomplement therapies may help.

Jennie Dusheck, M.A.
Mounting evidence suggests that the immune system’s ancient complement system plays a role in...
Drug Development, Laboratory Research

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