Multiple Sclerosis Discovery Forum

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New Findings | 22 Aug 2013

Phase 1 Trial of Stem Cells Begins in MS

The hope is that mesenchymal stem cell-derived neural progenitors will repair the damage wreaked by MS

Ricki Lewis, Ph.D.

Following investigational new drug approval by the U.S. Food and Drug Administration on August 24...

Clinical Research, Drug Development

New Findings | 19 Aug 2013

MS Cognitive Impairment Rates Lower Than Previously Reported

In a large MS group, cognitive impairment rates were unexpectedly low and few had severe impairment

Laurie Barclay, M.D.

In a large sample of persons with multiple sclerosis, rates of cognitive impairment were unexpectedly...

Clinical Research

New Findings | 12 Aug 2013

Plasma Osteopontin Levels: A New Marker for MS?

This study concluded that plasma osteopontin levels may be a marker for MS and neuromyelitis optica

Steven Fox

Elevated plasma osteopontin levels could prove to be a valuable biomarker not only for multiple sclerosis but also...

Clinical Research

New Findings | 12 Aug 2013

PUMA Protein May Underlie Oligodendroglial Cell Death in MS

A pro-apoptotic protein underlies oligodendroglial cell death in toxic demyelination and possibly in MS also

Laurie Barclay, M.D.

The PUMA protein (p53 upregulated modulator of apoptosis) underlies oligodendroglial cell death in...

Laboratory Research

New Findings | 9 Aug 2013

Gut Bacteria Boost Anti-Inflammatory Immune Cells in Mice

Compounds they produce while breaking down dietary fiber increase the number and function of regulatory T cells

Carol Cruzan Morton

Common compounds made by gut microbes that break down dietary fiber appear to boost the...

Laboratory Research

New Findings | 5 Aug 2013

More Signal Abnormalities Seen in Relatives of MS Patients

Relatives of people with MS have more white matter signal abnormalities than matched controls.

Steven Fox

Healthy relatives of people with multiple sclerosis demonstrate a higher frequency of white matter signal abnormalities and...

Clinical Research

New Findings | 5 Aug 2013

Anti-EBV Serology, HLA-DR Risk Profiles May Help Identify MS

Adding anti-EBV levels to HLA-DR risk profiles may significantly help discriminate MS cases from controls

Laurie Barclay, M.D.

Epstein-Barr virus serology and human leukocyte antigen-DR alleles may significantly help discriminate...

Clinical Research

News Synthesis | 5 Aug 2013

Harnessing Epitope Spreading to Treat MS

Echoes of a vanishing target reveal vulnerability

Ricki Lewis, Ph.D.

Like the mythical phoenix that rose from its ashes, a once-hot area of immunology research has...

Laboratory Research

Essays and Opinions | 2 Aug 2013

Easy Cognitive Assessments for People With MS

A new website helps clinicians interpret cognitive impairment tests in people with MS

Ralph H. B. Benedict, Ph.D., ABPP-CN

I am pleased to announce the unveiling of a free website offering the interpretation of...

Clinical Research

New Findings | 29 Jul 2013

Venocentric Lesions on MRI: An Early Marker of MS?

A review article suggests that venocentric lesions seen on MRI may be an early marker of MS

Steven Fox

Venocentric lesions seen on magnetic resonance imaging may be associated with future risk of...

Clinical Research