Multiple Sclerosis Discovery Forum

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Podcasts | 18 Mar 2016

Episode 70 with Dr. Brian Weinshenker on new diagnostic criteria for NMO

MSDF interviews Brian Weinshenker MD of the Mayo Clinic about new diagnostic criteria for neuromyelitis optica spectrum disorder and how it differs from MS. The new criteria build upon and broaden the definition of NMO.

MS Discovery

Clinical Research

News Briefs | 8 Mar 2016

Researchers Spill the Beans

An epidemiological link between coffee and MS raises new questions for future research

Carol Cruzan Morton

Coffee—a lot of it—is linked to a lower risk of multiple sclerosis, finds...

Clinical Research, Methods

Blogs | 6 Mar 2016

The MSDF Drug-Development Pipeline

The founder and curator of MSDF’s drug database reveals how it keeps you up to date with experimental and approved therapies in MS and related demyelinating diseases

Heather McDonald

Dozens of new MS drug-related developments are published in scientific papers or described in...

Clinical Research, Drug Development

Podcasts | 28 Feb 2016

Episode 69 with Dr. Alessandra Solari on information and decision tools for newly diagnosed patients

MS Discovery

Links to articles and other resources mentioned in Episode 69

Clinical Research, Methods

News Briefs | 27 Feb 2016

MS Research Roundup: 27 February 2016

FDA Fast-Tracks PPMS Drug Review; Molecular Target Runs Out of Air; Happy Accidents in the Lab; New Twist on Patient-Powered Research

Carol Cruzan Morton & Stephani Sutherland

Items of interest to multiple sclerosis researchers from around the Web...

Clinical Research, Drug Development, Laboratory Research, Meetings, People

New Findings | 24 Feb 2016

Lessons From Fingolimod for Primary Progressive Multiple Sclerosis

Fingolimod is ineffective for PPMS, but the phase 3 trial data may improve future studies

Stephani Sutherland

Even in failure, studies can be informative. Fingolimod, a disease-modifying treatment for relapsing-remitting multiple sclerosis, is...

Clinical Research, Drug Development, Meetings, Methods, People

Podcasts | 9 Feb 2016

Episode 68 with Dr. Philip De Jager on the state of MS genetics

MS Discovery

Links to articles and other resources mentioned in Episode 68

Methods

Essays and Opinions | 6 Feb 2016

Taking Studies of Sex Differences to the Next Level

Multiple sclerosis affects about three times more women than men, but pregnancy can protect against relapses, and MS in men tends to worsen faster. These naturally occurring sex differences could lead to new treatments—if they don’t stall on the way to the clinic.

Rhonda Voskuhl, MD

It is now over a year since the announcement of a new National Institutes of Health policy to encourage...

Clinical Research, Drug Development, Laboratory Research

News Synthesis | 2 Feb 2016

Will Death in French Drug Trial Lead to Tighter Phase 1 Rules?

While regulators are trying to figure out what went wrong, independent chemists have dug into the mechanism of what may have been a "dirty" drug

Madolyn Bowman Rogers

January saw one of the worst drug trial debacles in memory, when a healthy volunteer participating...

Clinical Research, Drug Development, Laboratory Research

Blogs | 26 Jan 2016

Podcasts discuss new MS treatment strategy

The MS Brain Health collection

Carol Cruzan Morton

No cure yet exists for MS, but a new therapeutic strategy may help extend brain health, delay progressive disease, and reduce future disability. That’s the assertion of a new report released at the October 2015 ECTRIMS meeting in Barcelona.

Clinical Research, Meetings