Time to Rethink CIS Criteria
About 20% of patients do not meet the diagnostic criteria of clinically isolated syndrome (CIS) based on radiological and clinical evidence. Patients who do not fit the CIS diagnostic criteria may yet have oligoclonal bands distinct to CSF, increased IgG synthesis rate and IgG index and must be treated as if they carried a diagnosis of CIS.
About 20% of patients do not meet the diagnostic criteria of clinically isolated syndrome (CIS) based on radiological and clinical evidence. Patients who do not fit the CIS diagnostic criteria may yet have oligoclonal bands distinct to CSF, increased IgG synthesis rate and IgG index and must be treated as if they carried a diagnosis of CIS.
It’s time to rethink the diagnostic criteria for clinically isolated syndrome. CIS is defined as...
Methods, People
