Multiple Sclerosis Discovery Forum

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The force awakens: insights into the origin and formation of microglia.
Characterisation of microglia during de- and remyelination: can they create a repair promoting environment?
The role of natural killer cells in multiple sclerosis and their therapeutic implications.
Episode 10 with Dr. Richard Ransohoff on his group's latest research
Assessment and Imaging of the Cerebrovascular Glycocalyx.
ForuMS: A Virtual Journal Club for MS Clinicians
17beta-estradiol and progesterone prevent cuprizone provoked demyelination of corpus callosum in male mice.
46th Annual WCBR Winter Conference on Brain Research
Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis.
US and EU regulatory authorities accept oral BG-12 marketing applications for review
Studies on the induction of hydrocephalus and spongy degeneration by cuprizone feeding and attempts to antidote the toxicity.
Efficacy of treatment of MS with IFNbeta-1b or glatiramer acetate by monthly brain MRI in the BECOME study.
White Matter Diffusion Changes during the First Year of Natalizumab Treatment in Relapsing-Remitting Multiple Sclerosis.
Exposure levels of anti-LINGO-1 Li81 antibody in the central nervous system and dose-efficacy relationships in rat spinal cord remyelination models after systemic administration.
TH1/TH2 Cytokine profile in relapsing-remitting multiple sclerosis patients treated with Glatiramer acetate or Natalizumab.
GlaxoSmithKline Product Development Pipeline
Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome.
Firategrast: natalizumab in a pill?
The effect of dimethyl fumarate (Tecfidera™) on lymphocyte counts: A potential contributor to progressive multifocal leukoencephalopathy risk.
Investigations with cultured human microglia on pathogenic mechanisms of Alzheimer's disease and other neurodegenerative diseases.
Swiss Analysis of Multiple Sclerosis: A Multicenter, Non-Interventional, Retrospective Cohort Study of Disease-Modifying Therapies.
Cerebellar cortical demyelination in the murine cuprizone model.
Dimethyl fumarate inhibits dendritic cell maturation via nuclear factor kcyB (NF-kcyB) and Extracellular Signal-regulated kinase 1 and 2 (ERK1/2) and Mitogen Stress activated kinase 1 (MSK1) signaling.
Δ⁹-tetrahydrocannabinol (Δ⁹-THC) exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.
Optical coherence tomography should be part of the routine monitoring of patients with multiple sclerosis: Yes.

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