Multiple Sclerosis Discovery Forum

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Episode 17 with Dr. Hans Lassmann on the usefulness of animal models for studying multiple sclerosis.
Studies on the induction of hydrocephalus and spongy degeneration by cuprizone feeding and attempts to antidote the toxicity.
Assessment and Imaging of the Cerebrovascular Glycocalyx.
MSGene
Myelin Oligodendrocyte Glycoprotein-Associated Pediatric Central Nervous System Demyelination: Clinical Course, Neuroimaging Findings, and Response to Therapy.
US and EU regulatory authorities accept oral BG-12 marketing applications for review
Characterisation of microglia during de- and remyelination: can they create a repair promoting environment?
Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis.
Exposure levels of anti-LINGO-1 Li81 antibody in the central nervous system and dose-efficacy relationships in rat spinal cord remyelination models after systemic administration.
Efficacy of treatment of MS with IFNbeta-1b or glatiramer acetate by monthly brain MRI in the BECOME study.
White Matter Diffusion Changes during the First Year of Natalizumab Treatment in Relapsing-Remitting Multiple Sclerosis.
Long-term efficacy and safety of transanal irrigation in multiple sclerosis.
Investigations with cultured human microglia on pathogenic mechanisms of Alzheimer's disease and other neurodegenerative diseases.
Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome.
The effect of dimethyl fumarate (Tecfidera™) on lymphocyte counts: A potential contributor to progressive multifocal leukoencephalopathy risk.
Episode 13 with Professor Alan Thompson on the International Progressive MS Alliance.
Episode 31 with Dr. Lloyd Kasper on the gut microbiome and MS
Firategrast: natalizumab in a pill?
Cerebellar cortical demyelination in the murine cuprizone model.
Cuprizone treatment induces demyelination and astrocytosis in the mouse hippocampus.
Dimethyl fumarate inhibits dendritic cell maturation via nuclear factor kcyB (NF-kcyB) and Extracellular Signal-regulated kinase 1 and 2 (ERK1/2) and Mitogen Stress activated kinase 1 (MSK1) signaling.
Comparative efficacy of switching to natalizumab in active multiple sclerosis.
Demyelination and Remyelination: From Mechanism to Therapy
The Fourth International Conference on Regulatory T Cells and TH Subsets and Clinical Applications in Human Disease
GlaxoSmithKline Product Development Pipeline

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