Multiple Sclerosis Discovery Forum

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Delayed visual evoked response in optic neuritis.
Comparative efficacy of interferon β versus glatiramer acetate for relapsing-remitting multiple sclerosis.
New diagnostic criteria for multiple sclerosis: guidelines for research protocols.
XI European Meeting on Glia Cells in Health and Disease
Effect of glatiramer acetate on conversion to clinically definite multiple sclerosis in patients with clinically isolated syndrome (PreCISe study): a randomised, double-blind, placebo-controlled trial.
Δ⁹-tetrahydrocannabinol (Δ⁹-THC) exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.
Breastfeeding is not related to postpartum relapses in multiple sclerosis.
Demyelination and Remyelination: From Mechanism to Therapy
US patent office grants patent claiming dosing regimen for TECFIDERA™ (dimethyl fumarate)
Neuroscience 2014
Novartis drug Gilenya® shows long-term efficacy and safety according to new data from extension of phase III head-to-head study
Cuprizone demyelination of the corpus callosum in mice correlates with altered social interaction and impaired bilateral sensorimotor coordination.
Population pharmacokinetics and pharmacodynamics of dalfampridine-ER in healthy volunteers and in patients with MS.
Estrogen controls vitamin D3-mediated resistance to experimental autoimmune encephalomyelitis by controlling vitamin D3 metabolism and receptor expression.
Oral BG-12 (dimethyl fumarate) significantly reduced multiple sclerosis (MS) relapses and disability progression in DEFINE Phase 3 clinical trial
Reduction of CD8+ T lymphocytes in multiple sclerosis patients treated with dimethyl fumarate
Age-related and cuprizone-induced changes in myelin and transcription factor gene expression and in oligodendrocyte cell densities in the rostral corpus callosum of mice.
Tumor necrosis factor alpha but not interleukin 1 beta mediates neuroprotection in response to acute nitric oxide excitotoxicity.
Cuprizone treatment induces demyelination and astrocytosis in the mouse hippocampus.
Neuroprotective dimethyl fumarate synergizes with immunomodulatory interferon beta to provide enhanced axon protection in autoimmune neuroinflammation.
Endocannabinoids in Multiple Sclerosis and Amyotrophic Lateral Sclerosis.
Episode 20 with Dr. Jeffrey Cohen discussing two MS-related clinical trials
Cerebroside synthesis as a measure of the rate of remyelination following cuprizone-induced demyelination in brain.
Cuprizone neurotoxicity in the rat: morphologic observations.
Glia in Health & Disease

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