Multiple Sclerosis Discovery Forum

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Episode 4 with Dr. Michael Racke on the Kir4.1 potassium channel
Frequency and magnitude of interferon β neutralizing antibodies in the evaluation of interferon β immunogenicity in patients with multiple sclerosis.
Exposure levels of anti-LINGO-1 Li81 antibody in the central nervous system and dose-efficacy relationships in rat spinal cord remyelination models after systemic administration.
Cuprizone treatment induces demyelination and astrocytosis in the mouse hippocampus.
Clinical Trials
Teriflunomide reduces behavioral, electrophysiological, and histopathological deficits in the Dark Agouti rat model of experimental autoimmune encephalomyelitis.
Comparative effectiveness of fingolimod versus interferons or glatiramer acetate for relapse rates in multiple sclerosis: a retrospective US claims database analysis.
Tumor necrosis factor alpha but not interleukin 1 beta mediates neuroprotection in response to acute nitric oxide excitotoxicity.
Clinical efficacy of BG-12 (dimethyl fumarate) in patients with relapsing-remitting multiple sclerosis: subgroup analyses of the DEFINE study.
Δ⁹-tetrahydrocannabinol (Δ⁹-THC) exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.
Relapses Requiring Intravenous Steroid Use and Multiple-Sclerosis-Related Hospitalizations: Integrated Analysis of the Delayed-Release Dimethyl Fumarate Phase III Studies.
SJL mice exposed to cuprizone intoxication reveal strain and gender pattern differences in demyelination.
Age-related and cuprizone-induced changes in myelin and transcription factor gene expression and in oligodendrocyte cell densities in the rostral corpus callosum of mice.
Demyelination and Remyelination: From Mechanism to Therapy
MS Research Roundup: An Introduction
Multiple sclerosis in Hispanics: a study of clinical disease expression.
Efficacy of treatment of MS with IFNbeta-1b or glatiramer acetate by monthly brain MRI in the BECOME study.
Assessment and Imaging of the Cerebrovascular Glycocalyx.
MS clinical trials: what can subgroup analyses teach us?
XI European Meeting on Glia Cells in Health and Disease
Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.
Effects of dimethyl fumarate on neuroprotection and immunomodulation.
Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination.
Observations on oligodendrocyte degeneration, the resolution of status spongiosus and remyelination in cuprizone intoxication in mice.
Cost-effectiveness of delayed-release dimethyl fumarate for the treatment of relapsing forms of multiple sclerosis in the United States.

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