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New Findings | 21 Sep 2012

Dimethyl Fumarate Shows Efficacy in Phase III Clinical Studies

Experimental oral drug tolerated relatively well

Carol Cruzan Morton

The first peer-reviewed phase III clinical trials of an experimental oral drug for the most common form...

Clinical Research, Drug Development

New Findings | 17 Sep 2012

Why TH17 Cells Turn to the Dark Side

Study identifies protein that spurs potential MS culprit to become pathogenic

Mitch Leslie

Whenever a criminal gets arrested, everyone asks why he went bad. Was it his upbringing? Did he...

Laboratory Research

New Findings | 13 Sep 2012

Brain booster

Fingolimod’s effects include neuronal production of BDNF

Stephani Sutherland

Side effects can sideline even the most successful drug. For fingolimod (Gilenya), the first oral therapy...

Laboratory Research

New Findings | 15 Aug 2012

Improper Inducements

Cells that orchestrate lymph node development might be culprits in MS

Mitch Leslie

Lymphoid tissue inducer (LTi) cells have been concealing a sinister secret. We’ve known them for...

Laboratory Research

New Findings | 1 Aug 2012

Split Personality

Can an Alzheimer culprit do good in MS?

Ingfei Chen and Emily Willingham

Being two-faced doesn’t usually enhance a reputation, but in the case of beta amyloid...

Laboratory Research

New Findings | 20 Jul 2012

Channeling MS

Immune response points toward cellular pores that allow potassium passage

Emily Willingham

Using antibodies as bait in a molecular fishing expedition, researchers have hooked a protein that...

Laboratory Research

New Findings | 13 Jul 2012

Fuel Injection

Myelin molecule transports sustenance to neurons

Stephani Sutherland

The myelin that encases axons is best known as an insulator, but new research shows...

Laboratory Research

New Findings | 10 Jul 2012

Untangling TNF Trouble

Genetic risk factor might explain harmful effects of failed MS therapy

Emily Willingham

Lurking within the human genome lies a single genetic letter that might reveal why...

Laboratory Research

New Findings | 14 Jun 2012

Fat Find

Molecules in myelin quell inflammation

Alla Katsnelson

Lipids compose the bulk of myelin, yet proteins have commanded the bulk of researchers’ attention...

Laboratory Research

New Findings | 8 Jun 2012

Petite but Potent

In autoimmune diseases, one microRNA might pack a powerful punch

Diana Gitig

Dousing the flames of autoimmunity poses a mighty challenge, but one tiny RNA could...

Laboratory Research