Comparative Effectiveness Research on the Treatment of Multiple Sclerosis: Request for Information from the Patient-Centered Outcomes Research Institute
Request For Information (RFI) Released: July 13, 2015
Information Due: July 27, 2015
For more information, email: info@pcori.org
Opportunity Snapshot
The Patient Centered Outcomes Research Institute has released a request for information (RFI) to identify patient registries and research groups with established cohorts of patients for potential collaborative research opportunities on comparative effectiveness research (CER) on the treatment of multiple sclerosis (MS) and to seek relevant input. PCORI is interested in supporting CER studies, including observational studies and/or randomized clinical trials that focus on the treatment of MS, with an emphasis on symptoms as outcomes. PCORI has consulted extensively with the MS community, including patients, clinicians and researchers, and with representatives of the pharmaceutical industry, private and public insurers to identify key research questions. PCORI has concluded that a large, representative cohort with extensive clinical information and the capacity to gather data directly from patients is a promising approach for conducting useful studies in this area. PCORI is therefore interested in obtaining information on the potential and the level of interest in collaborative research on topics identified by the stakeholder community. This opportunity is to provide information about the creation and participation in a 5-year collaborative effort that would result in a large number of patients with MS who would participate in observational longitudinal studies and randomized clinical trials. Teams of investigators would be invited to form a collaboration among clinical sites that include a large number of people with MS for observational studies and clinical trials focused on a specific set of CER questions. Read the RFI (.pdf)
Notice to Respondents
The Patient Centered Outcomes Research Institute (PCORI) issues this Request for Information (RFI) to obtain information on the data and resources as well as interest and capacity to develop and execute large scale collaborative research projects on the treatment of multiple sclerosis (MS). The intent of this RFI is to inform PCORI's CER research initiatives. While this RFI is open to all, PCORI is particularly interested in responses from organizations and individuals who have knowledge of and experience working with existing large patient registries and/or established patient cohorts oriented towards patient care and research on the treatments of MS. This request should not be construed as intent, commitment, or promise to acquire services, supplies, or solutions offered. No contract will directly result from any response to this RFI. PCORI will use the information submitted in response to this RFI at its discretion and will not provide comments to the responder's submission. Information learned from this RFI may be reflected in future PCORI research funding solicitation(s).
About PCORI
The Patient-Centered Outcomes Research Institute (PCORI) is a nonprofit organization headquartered in Washington, DC, with approximately 200 full-time employees. PCORI's purpose, as defined by the Patient Protection and Affordable Care Act of 2010, is to help patients, clinicians, purchasers, and policy makers make better-informed healthcare-related decisions and improve healthcare delivery and outcomes. PCORI achieves this goal by advancing the quality and relevance of evidence about how to prevent, diagnose, treat, monitor, and manage diseases, disorders, and other health conditions. PCORI promotes and helps to produce high-integrity and evidence-based information. Such information comes from research guided by patients, caregivers, and the broader healthcare community. PCORI is committed to transparency and a rigorous stakeholder-driven process that emphasizes patient engagement. PCORI uses a variety of forums and public comment periods to obtain public input throughout its operations. Read more at pcori.org
For more information, email: info@pcori.org