Papers: 9 Jan 2015 - 16 Jan 2015 Check out this week's papers from PubMed. If you are a member, please log in to recommend and comment on papers. If you are not a member, please register today and join the conversation. Papers: Editors' Pick Where is the causal variant? On the advantage of the family design over the case-control design in genetic association studies. Dandine-Roulland C, Perdry H Eur J Hum Genet. 2015 Jan 14. PMID: 25585700. Abstract Editors' Pick Heterogeneity of oligodendrocyte progenitor cells in adult human brain. Yuen Leong S, Rao VTS, Bin JM, Gris P, Sangaralingam M, Kennedy TE, Antel JP Ann Clin Transl Neurol. 2014 Apr; 1(4):272-83. Epub 2014 Mar 26. PMID: 25590039. Abstract Inflammasome-Induced IL-1β Secretion in Microglia Is Characterized by Delayed Kinetics and Is Only Partially Dependent on Inflammatory Caspases. Burm SM, Zuiderwijk-Sick EA, 't Jong AEJ, van der Putten C, Veth J, Kondova I, Bajramovic JJ J Neurosci. 2015 Jan 14; 35(2):678-87. PMID: 25589762. Abstract Optic Neuritis and the Visual Pathway: Evaluation of Neuromyelitis Optica Spectrum by Resting-State fMRI and Diffusion Tensor MRI. Lopes F C R, Alves-Leon S V, Godoy J M, de Souza Batista Scherpenhuijzen S, Fezer L, Gasparetto E L J Neuroimaging. 2015 Jan 15. PMID: 25588974. Abstract Appraisal of brain connectivity in radiologically isolated syndrome by modeling imaging measures. Giorgio A, Stromillo M L, De Leucio A, Rossi F, Brandes I, Hakiki B, Portaccio E, Amato M P, De Stefano N J Neurosci. 2015 Jan 14; 35(2):550-8. PMID: 25589750. Abstract SIRT1 Deficiency in Microglia Contributes to Cognitive Decline in Aging and Neurodegeneration via Epigenetic Regulation of IL-1β. Cho S-H, Chen JA, Sayed F, Ward ME, Gao F, Nguyen TA, Krabbe G, Sohn P D, Lo I, Minami S, et al. J Neurosci. 2015 Jan 14; 35(2):807-18. PMID: 25589773. Abstract Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis. Haanstra KG, Dijkman K, Bashir N, Bauer J, Mary C, Poirier N, Baker P, Scobie L, 't Hart BA, Vanhove B J Immunol. 2015 Jan 14. PMID: 25589073. Abstract Increased Circulating Levels of Vitamin D Binding Protein in MS Patients. Rinaldi A O, Sanseverino I, Purificato C, Cortese A, Mechelli R, Francisci S, Salvetti M, Millefiorini E, Gessani S, Gauzzi M C Toxins (Basel). 2015; 7(1):129-37. PMID: 25590278. Abstract c-kit plays a critical role in induction of intravenous tolerance in experimental autoimmune encephalomyelitis. Safavi F, Li H, Gonnella P, Mari E R, Rasouli J, Zhang G X, Rostami A Immunol Res. 2015 Jan 15. PMID: 25588867. Abstract Two Multiple Sclerosis Quality-of-Life Measures: Comparison in a National Sample. Moore F, Vickrey B, Fortin K, Lee L Can J Neurol Sci. 2015 Jan 14:1-9. PMID: 25586701. Abstract Transfer of Natalizumab into Breast Milk in a Mother with Multiple Sclerosis. Baker TE, Cooper SD, Kessler L, Hale TW J Hum Lact. 2015 Jan 13. PMID: 25586712. Abstract Brain-derived neurotrophic factor deficiency restricts proliferation of oligodendrocyte progenitors following cuprizone-induced demyelination. Tsiperson V, Huang Y, Bagayogo I, Song Y, VonDran MW, DiCicco-Bloom E, Dreyfus CF ASN Neuro. 2015 Jan; 7(1). PMID: 25586993. Abstract Resilience, self-efficacy, coping styles and depressive and anxiety symptoms in those newly diagnosed with multiple sclerosis. Tan-Kristanto S, Kiropoulos LA Psychol Health Med. 2015 Jan 14:1-11. PMID: 25588098. Abstract Alemtuzumab in the treatment of multiple sclerosis: key clinical trial results and considerations for use. Havrdova E, Horakova D, Kovarova I Ther Adv Neurol Disord. 2015 Jan; 8(1):31-45. PMID: 25584072. Abstract NLRP3 inflammasome is associated with the response to IFN-β in patients with multiple sclerosis. Malhotra S, Río J, Urcelay E, Nurtdinov R, Bustamante MF, Fernández O, Oliver B, Zettl U, Brassat D, Killestein J, et al. Brain. 2015 Jan 12. PMID: 25586466. Abstract Immunological differences between classical phenothypes of multiple sclerosis. Iwanowski P, Losy J J Neurol Sci. 2015 Jan 2. PMID: 25586536. Abstract Different MOG35-55 concentrations induce distinguishable inflammation through early regulatory response by IL-10 and TGF-β in mice CNS despite unchanged clinical course. Dias A T, Castro S B R D, De Souza Alves C C, Mesquita F P, De Figueiredo N S V, Evangelista M G, Castañon M C M N, Juliano M A, Ferreira A P Cell Immunol. 2015 Jan 7; 293(2):87-94. PMID: 25585346. Abstract Dimethyl fumarate in the treatment of relapsing-remitting multiple sclerosis: an overview. Bomprezzi R Ther Adv Neurol Disord. 2015 Jan; 8(1):20-30. PMID: 25584071. Abstract Repeated sugammadex usage in a patient with multiple sclerosis: a case report. Sinikoglu N, Totoz T, Gumus F, Karagulle O Wien Klin Wochenschr. 2015 Jan 14. Epub 2015 Jan 14. PMID: 25586446. Abstract Naringenin Suppresses Neuroinflammatory Responses Through Inducing Suppressor of Cytokine Signaling 3 Expression. Wu L-H, Lin C, Lin H-Y, Liu Y-S, Wu C Y-J, Tsai C-F, Chang P-C, Yeh W-L, Lu D-Y Mol Neurobiol. 2015 Jan 13. Epub 2015 Jan 13. PMID: 25579382. Abstract Transcriptional Regulation of Brain-Derived Neurotrophic Factor (BDNF) by Methyl CpG Binding Protein 2 (MeCP2): a Novel Mechanism for Re-Myelination and/or Myelin Repair Involved in the Treatment of Multiple Sclerosis (MS). KhorshidAhmad T, Acosta C, Cortes C, Lakowski TM, Gangadaran S, Namaka M Mol Neurobiol. 2015 Jan 13. Epub 2015 Jan 13. PMID: 25579386. Abstract Bee Venom Acupuncture Alleviates Experimental Autoimmune Encephalomyelitis by Upregulating Regulatory T Cells and Suppressing Th1 and Th17 Responses. Lee M J, Jang M, Choi J, Lee G, Min H J, Chung W-S, Kim J-I, Jee Y, Chae Y, Kim S-H, et al. Mol Neurobiol. 2015 Jan 13. Epub 2015 Jan 13. PMID: 25579380. Abstract lipid-specific IgM bands in csf associated with a reduced risk of developing pml during treatment with natalizumab. Villar LM, Costa-Frossard L, Masterman T, Fernandez O, Montalban X, Casanova B, Izquierdo G, Coret F, Tumani H, Saiz A, et al. Ann Neurol. 2015 Jan 7. PMID: 25581547. Abstract Disability Identity Predicts Lower Anxiety and Depression in Multiple Sclerosis. Bogart KR Rehabil Psychol. 2015 Jan 12. PMID: 25580882. Abstract Proteomics of a conundrum: thoughts on addressing the aetiology vs. progression of Multiple Sclerosis. Partridge MA, Myers SJ, Gopinath S, Coorssen JR Proteomics Clin Appl. 2015 Jan 8. PMID: 25580822. Abstract Learning a cost function for microscope image segmentation. Nilufar S, Perkins TJ Conf Proc IEEE Eng Med Biol Soc. 2014 Aug; 2014:5506-9. PMID: 25571241. Abstract Loss of Allograft inflammatory factor-1 ameliorates experimental autoimmune encephalomyelitis by limiting encephalitogenic CD4 T cell expansion. Chinnasamy P, Lutz SE, Riascos-Bernal DF, Jeganathan V, Casimiro I, Brosnan CF, Sibinga NES Mol Med. 2015 Jan 6. PMID: 25569805. Abstract Neuromyelitis optica in pregnancy complicated by posterior reversible encephalopathy syndrome, eclampsia and fetal death. Igel C, Garretto D, Robbins MS, Swerdlow M, Judge N, Dayal A J Clin Med Res. 2015 Mar; 7(3):193-5. Epub 2014 Dec 29. PMID: 25584107. Abstract A pilot study of an exercise-based patient education program in people with multiple sclerosis. Kersten S, Mahli M, Drosselmeyer J, Lutz C, Liebherr M, Schubert P, Haas CT Mult Scler Int. 2014; 2014:306878. Epub 2014 Dec 21. PMID: 25587449. Abstract KCHO-1, a Novel Antineuroinflammatory Agent, Inhibits Lipopolysaccharide-Induced Neuroinflammatory Responses through Nrf2-Mediated Heme Oxygenase-1 Expression in Mouse BV2 Microglia Cells. Lee D-S, Ko W, Yoon C-S, Kim D-C, Yun J, Lee J-K, Jun K-Y, Son I, Kim D-W, Song B-K, et al. Evid Based Complement Alternat Med. 2014; 2014:357154. Epub 2014 Dec 11. PMID: 25580149. Abstract Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination. Mohan H, Friese A, Albrecht S, Krumbholz M, Elliott CL, Arthur A, Menon R, Farina C, Junker A, Stadelmann C, et al. Acta Neuropathol Commun. 2014 Dec 11; 2(1):178. Epub 2014 Dec 11. PMID: 25589163. Abstract S1P signaling: new therapies and opportunities. Gonzalez-Cabrera PJ, Brown S, Studer SM, Rosen H F1000Prime Rep. 2014; 6:109. Epub 2014 Dec 01. PMID: 25580263. Abstract
Editors' Pick Where is the causal variant? On the advantage of the family design over the case-control design in genetic association studies. Dandine-Roulland C, Perdry H Eur J Hum Genet. 2015 Jan 14. PMID: 25585700. Abstract
Editors' Pick Heterogeneity of oligodendrocyte progenitor cells in adult human brain. Yuen Leong S, Rao VTS, Bin JM, Gris P, Sangaralingam M, Kennedy TE, Antel JP Ann Clin Transl Neurol. 2014 Apr; 1(4):272-83. Epub 2014 Mar 26. PMID: 25590039. Abstract
Inflammasome-Induced IL-1β Secretion in Microglia Is Characterized by Delayed Kinetics and Is Only Partially Dependent on Inflammatory Caspases. Burm SM, Zuiderwijk-Sick EA, 't Jong AEJ, van der Putten C, Veth J, Kondova I, Bajramovic JJ J Neurosci. 2015 Jan 14; 35(2):678-87. PMID: 25589762. Abstract
Optic Neuritis and the Visual Pathway: Evaluation of Neuromyelitis Optica Spectrum by Resting-State fMRI and Diffusion Tensor MRI. Lopes F C R, Alves-Leon S V, Godoy J M, de Souza Batista Scherpenhuijzen S, Fezer L, Gasparetto E L J Neuroimaging. 2015 Jan 15. PMID: 25588974. Abstract
Appraisal of brain connectivity in radiologically isolated syndrome by modeling imaging measures. Giorgio A, Stromillo M L, De Leucio A, Rossi F, Brandes I, Hakiki B, Portaccio E, Amato M P, De Stefano N J Neurosci. 2015 Jan 14; 35(2):550-8. PMID: 25589750. Abstract
SIRT1 Deficiency in Microglia Contributes to Cognitive Decline in Aging and Neurodegeneration via Epigenetic Regulation of IL-1β. Cho S-H, Chen JA, Sayed F, Ward ME, Gao F, Nguyen TA, Krabbe G, Sohn P D, Lo I, Minami S, et al. J Neurosci. 2015 Jan 14; 35(2):807-18. PMID: 25589773. Abstract
Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis. Haanstra KG, Dijkman K, Bashir N, Bauer J, Mary C, Poirier N, Baker P, Scobie L, 't Hart BA, Vanhove B J Immunol. 2015 Jan 14. PMID: 25589073. Abstract
Increased Circulating Levels of Vitamin D Binding Protein in MS Patients. Rinaldi A O, Sanseverino I, Purificato C, Cortese A, Mechelli R, Francisci S, Salvetti M, Millefiorini E, Gessani S, Gauzzi M C Toxins (Basel). 2015; 7(1):129-37. PMID: 25590278. Abstract
c-kit plays a critical role in induction of intravenous tolerance in experimental autoimmune encephalomyelitis. Safavi F, Li H, Gonnella P, Mari E R, Rasouli J, Zhang G X, Rostami A Immunol Res. 2015 Jan 15. PMID: 25588867. Abstract
Two Multiple Sclerosis Quality-of-Life Measures: Comparison in a National Sample. Moore F, Vickrey B, Fortin K, Lee L Can J Neurol Sci. 2015 Jan 14:1-9. PMID: 25586701. Abstract
Transfer of Natalizumab into Breast Milk in a Mother with Multiple Sclerosis. Baker TE, Cooper SD, Kessler L, Hale TW J Hum Lact. 2015 Jan 13. PMID: 25586712. Abstract
Brain-derived neurotrophic factor deficiency restricts proliferation of oligodendrocyte progenitors following cuprizone-induced demyelination. Tsiperson V, Huang Y, Bagayogo I, Song Y, VonDran MW, DiCicco-Bloom E, Dreyfus CF ASN Neuro. 2015 Jan; 7(1). PMID: 25586993. Abstract
Resilience, self-efficacy, coping styles and depressive and anxiety symptoms in those newly diagnosed with multiple sclerosis. Tan-Kristanto S, Kiropoulos LA Psychol Health Med. 2015 Jan 14:1-11. PMID: 25588098. Abstract
Alemtuzumab in the treatment of multiple sclerosis: key clinical trial results and considerations for use. Havrdova E, Horakova D, Kovarova I Ther Adv Neurol Disord. 2015 Jan; 8(1):31-45. PMID: 25584072. Abstract
NLRP3 inflammasome is associated with the response to IFN-β in patients with multiple sclerosis. Malhotra S, Río J, Urcelay E, Nurtdinov R, Bustamante MF, Fernández O, Oliver B, Zettl U, Brassat D, Killestein J, et al. Brain. 2015 Jan 12. PMID: 25586466. Abstract
Immunological differences between classical phenothypes of multiple sclerosis. Iwanowski P, Losy J J Neurol Sci. 2015 Jan 2. PMID: 25586536. Abstract
Different MOG35-55 concentrations induce distinguishable inflammation through early regulatory response by IL-10 and TGF-β in mice CNS despite unchanged clinical course. Dias A T, Castro S B R D, De Souza Alves C C, Mesquita F P, De Figueiredo N S V, Evangelista M G, Castañon M C M N, Juliano M A, Ferreira A P Cell Immunol. 2015 Jan 7; 293(2):87-94. PMID: 25585346. Abstract
Dimethyl fumarate in the treatment of relapsing-remitting multiple sclerosis: an overview. Bomprezzi R Ther Adv Neurol Disord. 2015 Jan; 8(1):20-30. PMID: 25584071. Abstract
Repeated sugammadex usage in a patient with multiple sclerosis: a case report. Sinikoglu N, Totoz T, Gumus F, Karagulle O Wien Klin Wochenschr. 2015 Jan 14. Epub 2015 Jan 14. PMID: 25586446. Abstract
Naringenin Suppresses Neuroinflammatory Responses Through Inducing Suppressor of Cytokine Signaling 3 Expression. Wu L-H, Lin C, Lin H-Y, Liu Y-S, Wu C Y-J, Tsai C-F, Chang P-C, Yeh W-L, Lu D-Y Mol Neurobiol. 2015 Jan 13. Epub 2015 Jan 13. PMID: 25579382. Abstract
Transcriptional Regulation of Brain-Derived Neurotrophic Factor (BDNF) by Methyl CpG Binding Protein 2 (MeCP2): a Novel Mechanism for Re-Myelination and/or Myelin Repair Involved in the Treatment of Multiple Sclerosis (MS). KhorshidAhmad T, Acosta C, Cortes C, Lakowski TM, Gangadaran S, Namaka M Mol Neurobiol. 2015 Jan 13. Epub 2015 Jan 13. PMID: 25579386. Abstract
Bee Venom Acupuncture Alleviates Experimental Autoimmune Encephalomyelitis by Upregulating Regulatory T Cells and Suppressing Th1 and Th17 Responses. Lee M J, Jang M, Choi J, Lee G, Min H J, Chung W-S, Kim J-I, Jee Y, Chae Y, Kim S-H, et al. Mol Neurobiol. 2015 Jan 13. Epub 2015 Jan 13. PMID: 25579380. Abstract
lipid-specific IgM bands in csf associated with a reduced risk of developing pml during treatment with natalizumab. Villar LM, Costa-Frossard L, Masterman T, Fernandez O, Montalban X, Casanova B, Izquierdo G, Coret F, Tumani H, Saiz A, et al. Ann Neurol. 2015 Jan 7. PMID: 25581547. Abstract
Disability Identity Predicts Lower Anxiety and Depression in Multiple Sclerosis. Bogart KR Rehabil Psychol. 2015 Jan 12. PMID: 25580882. Abstract
Proteomics of a conundrum: thoughts on addressing the aetiology vs. progression of Multiple Sclerosis. Partridge MA, Myers SJ, Gopinath S, Coorssen JR Proteomics Clin Appl. 2015 Jan 8. PMID: 25580822. Abstract
Learning a cost function for microscope image segmentation. Nilufar S, Perkins TJ Conf Proc IEEE Eng Med Biol Soc. 2014 Aug; 2014:5506-9. PMID: 25571241. Abstract
Loss of Allograft inflammatory factor-1 ameliorates experimental autoimmune encephalomyelitis by limiting encephalitogenic CD4 T cell expansion. Chinnasamy P, Lutz SE, Riascos-Bernal DF, Jeganathan V, Casimiro I, Brosnan CF, Sibinga NES Mol Med. 2015 Jan 6. PMID: 25569805. Abstract
Neuromyelitis optica in pregnancy complicated by posterior reversible encephalopathy syndrome, eclampsia and fetal death. Igel C, Garretto D, Robbins MS, Swerdlow M, Judge N, Dayal A J Clin Med Res. 2015 Mar; 7(3):193-5. Epub 2014 Dec 29. PMID: 25584107. Abstract
A pilot study of an exercise-based patient education program in people with multiple sclerosis. Kersten S, Mahli M, Drosselmeyer J, Lutz C, Liebherr M, Schubert P, Haas CT Mult Scler Int. 2014; 2014:306878. Epub 2014 Dec 21. PMID: 25587449. Abstract
KCHO-1, a Novel Antineuroinflammatory Agent, Inhibits Lipopolysaccharide-Induced Neuroinflammatory Responses through Nrf2-Mediated Heme Oxygenase-1 Expression in Mouse BV2 Microglia Cells. Lee D-S, Ko W, Yoon C-S, Kim D-C, Yun J, Lee J-K, Jun K-Y, Son I, Kim D-W, Song B-K, et al. Evid Based Complement Alternat Med. 2014; 2014:357154. Epub 2014 Dec 11. PMID: 25580149. Abstract
Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination. Mohan H, Friese A, Albrecht S, Krumbholz M, Elliott CL, Arthur A, Menon R, Farina C, Junker A, Stadelmann C, et al. Acta Neuropathol Commun. 2014 Dec 11; 2(1):178. Epub 2014 Dec 11. PMID: 25589163. Abstract
S1P signaling: new therapies and opportunities. Gonzalez-Cabrera PJ, Brown S, Studer SM, Rosen H F1000Prime Rep. 2014; 6:109. Epub 2014 Dec 01. PMID: 25580263. Abstract