Circulating PEG-indoleamine 2,3-dioxygenase ameliorates diverse inflammatory diseases without toxicity or compromising immunocompetence.

Simonovich JA, Clark RA, Kwiatkowski AJ, Fuchs MJ, Viso ME, Lu C, Macias SL, Pinto I, Shrestha AP, Ngo TB, et al.

Proc Natl Acad Sci U S A. 2026 Jul 14; 123(28):e2602536123. PMID: 42418487. Abstract