The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans. Menard L, Saadoun D, Isnardi I, Ng Y-S, Meyers G, Massad C, Price C, Abraham C, Motaghedi R, Buckner JH, et al. J Clin Invest. 2011 Sep; 121(9):3635-44. PMID: 21804190. Abstract CommentRecommendBookmarkWatch