Some comments on the relationship of the distribution of multiple sclerosis to latitude, solar radiation, and other variables.
This paper is often cited as the origin of the sunshine hypothesis and this is largely true, but it was temporally immediately after Dean and was undoubtedly derived from Dean’s observations in South Africa (Dean, 1949). However, Acheson was an adviser to Dean in this study as acknowledged at the end of the paper. Acheson, who subsequently became the chief medical officer for the U.K. and later dean of the Southampton Medical School, proposed at a Queen Square seminar that MS was related to sunshine deficiency. He was told by FMR Walshe, then the dean of the National Hospital, that it was “more likely to be moonshine,” the implication being that the young Acheson was under its influence.