Reduction in IL-10 producing B cells (Breg) in multiple sclerosis is accompanied by a reduced naïve/memory Breg ratio during a relapse but not in remission.
Knippenberg S, Peelen E, Smolders J, Thewissen M, Menheere P, Cohen Tervaert J W, Hupperts R, Damoiseaux J
J Neuroimmunol. 2011 Oct 28; 239(1-2):80-6. PMID: 21940055.Abstract
