Enantioselective total synthesis of the highly selective sphingosine-1-receptor VPC01091 by the Heck desymmetrization of a non-activated cyclopentene-fused spiro-pyrrolidinone.
Khan I U, Kattela S, Hassan A, Correia C R D
Org Biomol Chem. 2016 Oct 12; 14(40):9476-9480. PMID: 27722726.Abstract