Influence of Previous Failed Antispasticity Therapy on the Efficacy and Tolerability of THC:CBD Oromucosal Spray for Multiple Sclerosis Spasticity. Haupts M, Vila C, Jonas A, Witte K, Álvarez-Ossorio L Eur Neurol. 2016 May 10; 75(5-6):236-243. Epub 2016 May 10. PMID: 27160412. Abstract CommentRecommendBookmarkWatch