Antibody producing B lineage cells invade the central nervous system predominantly at the time of and triggered by acute Epstein-Barr virus infection: A hypothesis on the origin of intrathecal immunoglobulin synthesis in multiple sclerosis. Otto C, Hofmann J, Ruprecht K Med Hypotheses. 2016 Jun; 91:109-13. Epub 2016 Apr 16. PMID: 27142157. Abstract CommentRecommendBookmarkWatch