Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain.
Schmitt C, Strazielle N, Ghersi-Egea J-F
J Neuroinflammation. 2012 Aug 7; 9(1):187. Epub 2012 Aug 07. PMID: 22870891.Abstract