Multiple Sclerosis Discovery Forum

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Biogen Idec receives notification of PDUFA date extension for PLEGRIDY™ (peginterferon beta-1a)
Do oligoclonal bands add information to MRI in first attacks of multiple sclerosis?
How many injections did you miss last month? A simple question to predict interferon β-1a adherence in multiple sclerosis.
Subcutaneous recombinant interferon-β-1a (Rebif®): a review of its use in the treatment of relapsing multiple sclerosis.
Progressive Multifocal Leukoencephalopathy: Why Gray and White Matter.
Rituximab Efficiently Depletes Increased CD20-Expressing T Cells in Multiple Sclerosis Patients.
Combination therapy of interferon Beta-1b and tacrolimus: a pilot safety study.
Dimethyl fumarate inhibits integrin α4 expression in multiple sclerosis models.
Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis. European Study Group on interferon beta-1b in secondary progressive MS.
Flupirtine: pharmacology and clinical applications of a nonopioid analgesic and potentially neuroprotective compound.
From Bugs to Brains: the gut microbiome in neurological health
Randomized controlled trial of interferon- beta-1a in secondary progressive MS: Clinical results.
Transdermal Application of Myelin Peptides in Multiple Sclerosis Treatment.
Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation.
Berlex continues legal challenge to FDA over MS drug.
Clinical and MRI predictors of response to interferon-beta and glatiramer acetate in relapsing-remitting multiple sclerosis patients.
Interferon-beta stabilizes barrier characteristics of the blood-brain barrier in four different species in vitro.
CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells.
The effects of teriflunomide on lymphocyte subpopulations in human peripheral blood mononuclear cells in vitro.
IL-17 and GM-CSF Expression Are Antagonistically Regulated by Human T Helper Cells.
Gordon Research Conference on Synaptic Dysfunction and Neurodegeneration
Flupirtine shows functional NMDA receptor antagonism by enhancing Mg2+ block via activation of voltage independent potassium channels. Rapid communication.
NF-κB transcriptional activation by TNFα requires phospholipase C, extracellular signal-regulated kinase 2 and poly(ADP-ribose) polymerase-1.
Cannabinoids for Medical Use: A Systematic Review and Meta-analysis.
Flupirtine

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