Multiple Sclerosis Discovery Forum

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Neuroinflammation increases GABAergic tone and impairs cognitive and motor function in hyperammonemia by increasing GAT-3 membrane expression. Reversal by sulforaphane by promoting M2 polarization of microglia.
Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein.
Getting a Handle on Lymphopenia With Tecfidera
Interferon beta-1b in secondary progressive MS: results from a 3-year controlled study.
Dimethyl fumarate (BG-12, Tecfidera) - NICE says yes in draft final guidance
Monomethyl fumarate augments NK cell lysis of tumor cells through degranulation and the upregulation of NKp46 and CD107a.
Effect of disease duration on personality type in multiple sclerosis patients and healthy individual.
Magnetization transfer ratio in the delayed-release dimethyl fumarate DEFINE study.
Optic neuritis: a 5-year follow-up study of Chinese patients based on aquaporin-4 antibody status and ages.
Emerging oral agents for multiple sclerosis.
Beneficial actions of the anti-inflammatory dimethyl fumarate in glioblastomas.
Inhibition of dihydroorotate dehydrogenase by the immunosuppressive agent leflunomide.
Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. The IFNB Multiple Sclerosis Study Group.
Interferon beta-1b therapy in chronic viral dilated cardiomyopathy--is there a role for specific therapy?
Epigenetic Modulation of Human Induced Pluripotent Stem Cell Differentiation to Oligodendrocytes.
8th International Congress on Autoimmunity
Biogen Idec reports death of patient on its MS pill
Multiple sclerosis and risk of young-adult-onset Hodgkin lymphoma.
Long-term genome-wide blood RNA expression profiles yield novel molecular response candidates for IFN-beta-1b treatment in relapsing remitting MS.
Genpharm and Genzyme Aubagio ® agreement for the MENA region
The impact of multiple sclerosis relapse treatment on migration of effector T cells - Preliminary study.
EU regulator warns on possible MS drugs side effects
Ethnicity and prevalence of multiple sclerosis in east London.
Visualizing Non-Gaussian Diffusion: Clinical Application of q-Space Imaging and Diffusional Kurtosis Imaging of the Brain and Spine.
Intravenous mitoxantrone and cyclophosphamide as second-line therapy in multiple sclerosis: an open-label comparative study of efficacy and safety.

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