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Laboratory Research

Comorbidities, Both Physical and Mental, Are Pervasive in MS

Comorbidity Figure 1
Individuals with MS have excessive rates of physical and mental health comorbidities, which can affect health-related quality of life

The link between multiple physical comorbidities and mental health comorbidities is strong among Scottish people with MS, according to findings from a cross-sectional analysis published in BMC Neurology.

 

Clinical Research, Drug Development, Laboratory Research, Meetings, Methods, People

MS Research Roundup: May 27, 2014

Research Roundup logo
Sex, Drugs, and Preclinical Research; Promising Biomarker for Progressive MS; Journalist With MS Finds Hope in Stem Cell Trial
Items of interest to multiple sclerosis researchers from around the Web...
Clinical Research, Drug Development, Laboratory Research, People

Blood Serum From Relapsing MS Patients May Damage the Blood-Brain Barrier

When Patterns Break
Serum from relapsing MS patients reduced cultured brain cells’ expression of tight junction molecules and increased the expression of cell adhesion molecules that promote cytokine-activated leukocyte migration. If these serum factors are also present in plasma or whole blood, the research raises questions about the safety of blood donations from people with MS.
When cultured cells of the blood-brain barrier are treated with serum from MS patients...
Laboratory Research

Nasal Vaccine May Be Effective for SPMS

Nasal vaccine
A study in a mouse model of secondary progressive multiple sclerosis suggests that a nasal vaccine that regulates innate immunity may halt clinical disease and neurodegeneration
Most multiple sclerosis patients are initially diagnosed with the relapsing-remitting form of the disease, but over time...
Laboratory Research, Meetings

Low-Dose Naltrexone and Met-Enkephalin Improve EAE Mice

Naltrexone
Widely touted in multiple sclerosis patient communities, low-dose naltrexone does appear to improve disease scores in about half of mice with an experimentally induced version of MS. Researchers found a similar pattern of results with met-enkephalin.
A growing subculture of MS patients and clinicians has been touting low-dose...
Clinical Research, Drug Development, Laboratory Research, Meetings

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