Skip to main content
Multiple Sclerosis Discovery Forum

Multiple Sclerosis Discovery Forum

Inspiring Connections

Utility Navigation

  • Feedback
  • Newsletter
  • RSS
  • Twitter

User Top Menu

  • Welcome, guest
  • Log In
  • Join
  • Why Join?

Search form

  • About Us
    • Overview
    • Who We Are
    • Contact
    • Fan Mail
    • How to Cite
  • News & Future Directions
    • New Findings
    • News Briefs
    • Podcasts
    • News Synthesis
    • Essays & Opinions
    • Blogs
  • Papers
    • Editors' Picks
    • Classic Papers
    • Archive
  • Forums
    • Discussions
    • Webinars
  • Professional Resources
    • Meetings & Events
      • Past Meetings
    • Funding Opportunities
    • Jobs
    • Member Directory
    • Bulletin Board
    • Useful Links
  • Research Resources
    • Data Visualizations
      • Clinical Trials - Public Availability of Results
      • World Map
      • MS trials baseline
      • NMO History
      • NMO Galaxy
      • Map of MS Prevalence
      • Progressive MS Authors Galaxy
      • Word Cloud
      • MSLine
      • Ongoing Clinical Trials in MS
      • MRI-Related Clinical Trials
      • RRMS and CIS
      • Immunopathogenesis of MS
      • The MS Galaxy
      • ARR in Placebo Groups
      • Symptoms Prevalence
      • Scientific Literature TreeMap
      • Clinical Trials in MS
    • Drug-Development Pipeline
    • Tissue Repositories
    • MSGene
    • Animal Models
    • Clinical Trials
  • Click Here to Support MSDF

You are here

Home » Research Resources » Data Visualizations » Clinical Trials in Multiple Sclerosis

Research Resources

  • Data Visualizations
    • Clinical Trials - Public Availability of Results
    • World Map
    • MS trials baseline
    • NMO History
    • NMO Galaxy
    • Map of MS Prevalence
    • Progressive MS Authors Galaxy
    • Word Cloud
    • MSLine
    • Ongoing Clinical Trials in MS
    • MRI-Related Clinical Trials
    • RRMS and CIS
    • Immunopathogenesis of MS
    • The MS Galaxy
    • ARR in Placebo Groups
    • Symptoms Prevalence
    • Scientific Literature TreeMap
    • Clinical Trials in MS
  • Drug-Development Pipeline
  • Tissue Repositories
  • MSGene
  • Animal Models
  • Clinical Trials

Clinical Trials in Multiple Sclerosis

Developed by Khawai.

Background

Within the past 30 years, new and effective therapies have been developed for the treatment of multiple sclerosis (MS). Since 1993, several compounds have been granted marketing authorization for relapsing-remitting MS patients: IFNβ-1a, IFNβ-1b, glatiramer acetate (GA), mitoxantrone, natalizumab, fingolimod and teriflunomide.

Data display

The below interactive bubble chart presents key features of the 106 clinical trials in MS that have been reported between 1985 and April 2014 in the scientific literature (New England Journal of Medicine, Lancet, Lancet Neurology, Neurology, etc). The cumulative number of patients who have been involved in these trials i.e. who have contributed to therapeutic breakthroughs in MS, is 44606.


Data source: click here to download the database (csv format)


Mouse over the bubbles to learn more about each trial and switch tabs!
Note: This chart runs on modern browsers (Chrome, Safari, Firefox, and Internet Explorer>8).

All Trials By Compound By Phase By Population By Nb Dose By Year By Funding

About Bubble Charts

A bubble chart typically displays data triplets (x, y, z) corresponding to three continuous variables: x and y to define the position, and z, the radius of each bubble. In our example, x and y coordinates are optimized according to an algorithm which essentially balances bubble's gravity (i.e.action of moving towards the center of the plot), friction (i.e.velocity decay), and charge (or repulsion/attraction force). This layout is frequently used for network visualization [1]. In addition to x, y and z, it is possible to encode other information. For instance, the color coding tell us about the trial outcome (positive, negative or 'other'), while each tab provides a different view of what the trials breakdown looks like. So, the current webpage displays data from 106 clinical trials, in 7 different ways.

[1] Gibson H., Faith J., Vickers P. A survey of two-dimensional graph layout techniques for information visualization. Information Visualization, 2012, in press.

MSDF Footer

Copyright © 2014 MGH and ACP
  • Privacy
  • Terms of Use
  • How to Cite
  • FAQ/Help
  • Site Map
  • Support Us
  • Feedback
  • Image Credits
All site content, except where otherwise noted, is licensed under a Creative Commons BY license. Please let us know where and how you use MSDF material.

Content By

Software By