MS Patient, Ph.D.
A new blog series
Today we begin a new feature here at MSDF: a series of blog posts we’re calling...
Clinical Research, Drug Development, Laboratory Research, Methods, People
Laboratory Research
Study Reveals New Facets of NMO Pathophysiology
Blood-brain barrier modeled in coculture system
Once thought to be a variant of multiple sclerosis, neuromyelitis optica bears similar pathophysiology to...
Laboratory Research, Meetings
High Noon at the Th17 Corral
Inflammatory immune cells in mice keep time with circadian clock
The fate of one of the key inflammatory immune cell types implicated in the brain attacks that result in multiple sclerosis is tied to...
Laboratory Research
Early-Detection Probe for MS Exploits Coagulation Protein
An activatable cell-penetrating peptide accumulates with thrombin activity in EAE mice
Researchers reported that they have developed an early-detection system for MS that could soon be used to...
Laboratory Research, Meetings, Methods
Anti-Inflammatory Apolipoprotein May Protect Against MS Symptoms
ApoA1-deficient mice have worse symptoms than wild-type mice in the EAE model of MS
Apolipoprotein A1, a major component of high-density lipoprotein—otherwise known as good cholesterol—provides...
Laboratory Research, Meetings
National MS Society Partners With Accelerated Cure Project Online Forum to Drive Progress
Society providing funding for MS Discovery Forum to drive research connections in progressive MS for researchers and clinicians
The National Multiple Sclerosis Society is partnering with the Accelerated Cure Project's Multiple Sclerosis Discovery Forum...
Clinical Research, Drug Development, Laboratory Research, Meetings, Methods, People
Stem Cells Stop the Train of MS Damage in Mice
Neural precursors derived from mature tissues rebuild myelin in mice with experimental autoimmune encephalomyelitis
Stem cells grown from mature cells stem the tide of myelin destruction in mice with...
Laboratory Research
Old Drug May Wield New Power
Benztropine boosts the number and the activity of myelin-making cells in animals
In findings that may speed the search for drugs that can postpone or prevent...
Drug Development, Laboratory Research
Ultrahigh-Field MRI May Detect Additional Pathology in EAE
In a mouse model of MS, ultrahigh-field MRI detected lesions not visible with conventional MRI. The technique also detected signs of spinal cord ischemia in human patients with MS.
Ultrahigh-field magnetic resonance imaging may detect pathological changes not visible with conventional MRI, according to...
Clinical Research, Laboratory Research
Neuromyelitis Optica, Part 4: Unresolved Questions
And finally, a look at some unresolved questions, such as people diagnosed with NMO who don’t have the aquaporin antibody, and the funding situation
A recent study that compared several antibody assays found that about a quarter of patients diagnosed with NMO lack...
Clinical Research, Drug Development, Laboratory Research, People
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