PBPK Modeling and Clinical Data Reveal Reduced Impact of CYP3A4 and CYP2C9 Inhibitors on Elimination of Siponimod.

Huth F, Shakeri-Nejad K, Gardin A, Shah B, Pohl O, Pezous N, Faller T

Clin Transl Sci. 2026 Jul; 19(7):e70657. PMID: 42364973. Abstract