Multiple Sclerosis Discovery Forum

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Targeting non-apoptotic regulated cell death (RCD) to treat neurodegenerative diseases.
Psychological correlates of suicidal ideation in people with multiple sclerosis: a cross-sectional study.
Beyond GLM: Inter-Subject Variability as a Complementary Approach to Detect Longitudinal Changes in Emotion Processing in Multiple Sclerosis.
Eosinophil Recruitment and Activity in CNS Lesions of MOG Antibody-Associated Myelitis Following Influenza Vaccination: A Case Report.
Longitudinal Repeatome Remodeling in Peripheral Blood Following Parkinson's Disease Diagnosis.
Molecular Target Discovery and Systemic Mechanism Analysis of Teriflunomide for Dry Eye Disease.
Vocational rehabilitation for people with multiple sclerosis: A systematic scoping review of international evidence.
TNF-α blockers and demyelinating lesions in pediatric non-infectious uveitis: Insights from a real world cohort.
Multikingdom microbiome-based machine learning enables multiple sclerosis diagnosis.
Mechanobiology of Myelin Generation/Regeneration in Health and Disease.
The Relationship between Antibody-mediated Immune Responses and Four Types of Neurodegenerative Diseases: A Mendelian Randomization Analysis.
Bcl-2 as a Double-edged Sword for the Treatment of Multiple Sclerosis: A Systematic Review.
The Myelin-Derived Peptide NSDP1 Suppresses Neuroinflammation and Attenuates Demyelination in Chronic Cuprizone-Fed Mice via Modulation of cGAS-STING Signaling.
Epigenetic and genetic insights for tailored therapeutic strategies in multiple sclerosis.
Quantitative MRI Biomarkers of Myelin: Cross-Validation and Diagnostic Performance in Multiple Sclerosis.
Translating B-Cell and Plasma-Cell Targeting from Oncology to Autoimmunity: Modalities, Quantitative Bridging, and a Development Roadmap.
Nanoparticle-delivered immunomodulators targeting blood-brain barrier disruption in fulminant adult-onset ADEM.
Nitric oxide in neuroinflammation and neurodegeneration: dual roles, inflammasome crosstalk, and biomarker opportunities.
A Pre-symptomatic phase of tumefactive multiple sclerosis mirrors radiologically isolated syndrome.
Metabolomic Signatures of Brain Atrophy and Ibudilast Response in Progressive Multiple Sclerosis.
CYP46A1-Targeted Treatment Alleviates Long-Term White Matter Injury Following Traumatic Brain Injury by Promoting Cholesterol Metabolic Clearance and Remyelination.
Metformin attenuates cuprizone-induced mitochondrial dysfunction and senescence-associated changes in primary neuronal cells.
Discovery of 4-((2S,5R)-2-((difluoromethoxy)methyl)-5-(4-(trifluoromethyl)phenyl)piperidin-1-yl)-N-((R)-1-(4-(ethylsulfonyl)phenyl)-2-hydroxyethyl)benzamide as a potent, orally available RORγt inverse agonist.
Large language models to infer depression in patients with neurological conditions.
Annexin A1 and its membrane receptor complex: Implications for immune regulation and autoimmune disease mechanisms.

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