Multiple Sclerosis Discovery Forum

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Neuroendothelial NMDA receptors as therapeutic targets in experimental autoimmune encephalomyelitis.
No evidence for increased brain iron deposition in patients with ischemic white matter disease.
FTY720-Induced Lymphopenia does not Aggravate Mortality in a Murine Model of Polymicrobial Abdominal Sepsis.
Nrf2-dysregulation correlates with reduced synthesis and low glutathione levels in experimental autoimmune encephalomyelitis.
Donepezil promotes differentiation of neural stem cells into mature oligodendrocytes at the expense of astrogenesis.
To fingolimod and beyond: The rich pipeline of drug candidates that target S1P signaling.
Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentiation by Inducing the Expression of Eomes.
Natalizumab treatment leads to an increase in circulating CXCR3-expressing B cells.
Extracellular Vesicles from Vascular Endothelial Cells Promote Survival, Proliferation and Motility of Oligodendrocyte Precursor Cells.
Involvement of the IL-1 system in experimental autoimmune encephalomyelitis and multiple sclerosis: Breaking the vicious cycle between IL-1β and GM-CSF.
Rationale, design, and methods of a non-interventional study to establish safety, effectiveness, quality of life, cognition, health-related and work capacity data on Alemtuzumab in multiple sclerosis patients in Germany (TREAT-MS).
Cholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling.
Adherence and persistence to drug therapies for multiple sclerosis: A population-based study.
Clinical Profiles and Short-Term Outcomes of Acute Disseminated Encephalomyelitis in Adult Chinese Patients.
Cognitive impairment among patients with multiple sclerosis: associations with employment and quality of life.
A new role for the P2Y-like GPR17 receptor in the modulation of multipotency of oligodendrocyte precursor cells in vitro.
A genetic basis for multiple sclerosis severity: Red herring or real?
Treatment of surgical brain injury by immune tolerance induced by intrathymic and hepatic portal vein injection of brain antigens.
Effect of interferon-β1α therapy on multiple sclerosis based on gadolinium-enhancing or active T2 magnetic resonance imaging outcomes: a meta-analysis.
Chronic iron overload induces gender-dependent changes in iron homeostasis, lipid peroxidation and clinical course of experimental autoimmune encephalomyelitis.
Synergistic and Superimposed Effect of Bone Marrow-Derived Mesenchymal Stem Cells Combined with Fasudil in Experimental Autoimmune Encephalomyelitis.
Increased inflammasome related gene expression profile in PBMC may facilitate T helper 17 cell induction in multiple sclerosis.
Activated CD4+ and CD8+ T Cell Proportions in Multiple Sclerosis Patients.
A high throughput drug screening assay to identify compounds that promote oligodendrocyte differentiation using acutely dissociated and purified oligodendrocyte precursor cells.
MicroRNA-155 enhances T cell trafficking and antiviral effector function in a model of coronavirus-induced neurologic disease.

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