Multiple Sclerosis Discovery Forum

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Mycophenolic acid inhibits IL-2-dependent T cell proliferation, but not IL-2-dependent survival and sensitization to apoptosis.
INF-β1b therapy modulates L-arginine and nitric oxide metabolism in patients with relapse remittent multiple sclerosis.
Episode 46 with Dr. Hans Lassmann on biomarkers in NMO and MS
An RNA profile identifies two subsets of multiple sclerosis patients differing in disease activity.
Equivalent Gene Expression Profiles between Glatopa™ and Copaxone®.
Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells.
Autoimmune tolerance eliminates relapses but fails to halt progression in a model of multiple sclerosis.
20th Annual Rehabilitation In Multiple Sclerosis (RIMS) Conference
Estriol preserves synaptic transmission in the hippocampus during autoimmune demyelinating disease.
Structure of the LINGO-1-anti-LINGO-1 Li81 antibody complex provides insights into the biology of LINGO-1 and the mechanism of action of the antibody therapy.
Episode 44 with Dr. Monika Bradl on an animal model for neuromyelitis optica (NMO)
Paternal therapy with disease modifying drugs in multiple sclerosis and pregnancy outcomes: a prospective observational multicentric study.
American Society for Neurochemistry 47th Annual Meeting
Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects.
Suppression of CD4+ T cell activation by a novel inhibitor of Src family kinases.
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Episode 55 with Dr. Michael Levy on the status of regenerative stem cell therapies for multiple sclerosis
Direct immunomodulatory influence of IFN-β on human astrocytoma cells.
An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation.
Episode 61 with Dr. Yanming Wang on molecular imaging of the myelin sheathing of axons
Heartbleed Bug
Invitation to Share Your Thoughts on a New MS Research Resource
XVI European Charcot Foundation lecture: nutrition and environment, can MS be prevented?
No evidence of disease activity: indirect comparisons of oral therapies for the treatment of relapsing-remitting multiple sclerosis.
Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex.

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