Multiple Sclerosis Discovery Forum

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TGFβ Signaling Regulates the Timing of CNS Myelination by Modulating Oligodendrocyte Progenitor Cell Cycle Exit through SMAD3/4/FoxO1/Sp1.
Impact of cladribine on soluble adhesion molecules in multiple sclerosis.
Temporal relationship between elevation of epstein-barr virus antibody titers and initial onset of neurological symptoms in multiple sclerosis.
Interferon β-1b directly modulates human neural stem/progenitor cell fate.
Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid.
Treatment Optimization in MS: Canadian MS Working Group Updated Recommendations.
New York Academy of Sciences: T Cells at the Interface of Immune-CNS Cross-Talk
Development of experimental autoimmune encephalomyelitis (EAE) in mice requires vitamin D and the vitamin D receptor.
Vitamin D receptor-retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation.
Glatiramer acetate (Copaxone) induces degenerate, Th2-polarized immune responses in patients with multiple sclerosis.
Effect of Glatiramer Acetate on Peripheral Blood Brain-Derived Neurotrophic Factor and Phosphorylated TrkB Levels in Relapsing-Remitting Multiple Sclerosis.
Dose titration of BAF312 attenuates the initial heart rate reducing effect in healthy subjects.
American Academy of Neurology Annual Meeting
Clinically feasible MTR is sensitive to cortical demyelination in MS.
[Results of a comparative clinical trial of the Russian Β - interferon-1b bioanalogue (infibeta)].
Receptos doses first patient in Phase 2/3 trial for RPC1063 in multiple sclerosis
Rituximab versus fingolimod after natalizumab in multiple sclerosis patients.
The challenge of comorbidity in clinical trials for multiple sclerosis.
Development of cladribine at Scripps for hairy cell leukemia and current results.
Revimmune (High-Dose Cyclophosphamide) for Autoimmune Diseases
Individual axons regulate the myelinating potential of single oligodendrocytes in vivo.
GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus: a first-in-humans randomized clinical study.
Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis.
Immunomodulatory therapeutic effect of glatiramer acetate on several murine models of inflammatory bowel disease.
Santhera's Phase III program with Catena®/Raxone® in Duchenne muscular dystrophy on track to deliver pivotal data early in 2Q 2014

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