Multiple Sclerosis Discovery Forum

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Serum from interferon-β-1b-treated patients with early multiple sclerosis stabilizes the blood-brain barrier in vitro.
Dimethyl fumarate (BG-12, Tecfidera) - NICE gives initial "no" decision
Monomethyl fumarate augments NK cell lysis of tumor cells through degranulation and the upregulation of NKp46 and CD107a.
Breastfeeding and multiple sclerosis.
New data from ENDORSE show positive results continued over five years with TECFIDERA® (dimethyl fumarate) in a wide range of multiple sclerosis patients
Results from the 5-year, phase IV RENEW (Registry to Evaluate Novantrone Effects in Worsening Multiple Sclerosis) study.
Changes of serum sICAM-1 and MMP-9 induced by rIFNbeta-1b treatment in relapsing-remitting MS.
Role of regulatory b cells in neuroimmunologic disorders.
Teva Announces U.S. Supreme Court Decision to Reverse Federal Circuit Court’s Judgment on COPAXONE® 20 mg/mL Case and Remand for Further Review
Gordon Research Conference on Glia Biology: Functional Interactions among Glia & Neurons
First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models.
Equivalence of Generic Glatiramer Acetate in Multiple Sclerosis: A Randomized Clinical Trial.
Gpr126 is essential for peripheral nerve development and myelination in mammals.
One calcitriol dose transiently increases Helios(+)FoxP3(+) T cells and ameliorates autoimmune demyelinating disease.
Oral ponesimod in relapsing-remitting multiple sclerosis: a randomised phase II trial.
Plasma osteopontin levels are associated with disease activity in the patients with multiple sclerosis and neuromyelitis optica.
Incorporating Alcohol Pharmacotherapies Into Medical Practice
Pervasive Axonal Transport Deficits in Multiple Sclerosis Models.
CXCR7 Is Involved in Human Oligodendroglial Precursor Cell Maturation.
TGFβ Signaling Regulates the Timing of CNS Myelination by Modulating Oligodendrocyte Progenitor Cell Cycle Exit through SMAD3/4/FoxO1/Sp1.
Pharmacodynamics of Dimethyl Fumarate are Tissue-specific and Involve NRF2-dependent and -independent Mechanisms.
Biogen Idec completes purchase of full rights and control of Tysabri®
Risks of immune system treatments.
Treatment Optimization in MS: Canadian MS Working Group Updated Recommendations.
Glatiramer acetate biases dendritic cells towards an anti-inflammatory phenotype by modulating OPN, IL-17, and RORγt responses and by increasing IL-10 production in experimental allergic encephalomyelitis.

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