Multiple Sclerosis Discovery Forum

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Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.
Optical Coherence Tomography in Multiple Sclerosis.
Rebif approval application
Specific inhibition of secreted NRG1 types I-II by heparin enhances Schwann Cell myelination.
WT1 and interferon-β-vitamin D association in MS: a longitudinal study.
Natalizumab plus interferon beta-1a for relapsing multiple sclerosis.
Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand.
Microglia across the lifespan: from origin to function in brain development, plasticity and cognition.
Differential transcriptional response profiles in human myeloid cell populations.
Urinary incontinence in multiple sclerosis: prevalence, severity and impact on patients' quality of life.
A silver lining of neuroinflammation: Beneficial effects on myelination.
Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites.
Biomarkers of disease activity in multiple sclerosis.
LINGO-1, A TRANSMEMBRANE SIGNALING PROTEIN, INHIBITS OLIGODENDROCYTE DIFFERENTIATION AND MYELINATION THROUGH INTERCELLULAR SELF-INTERACTIONS.
Clinically isolated syndromes.
A monoclonal natural human IgM protects axons in the absence of remyelination.
Effect of oral cladribine on time to conversion to clinically definite multiple sclerosis in patients with a first demyelinating event (ORACLE MS): a phase 3 randomised trial.
FDA product review for daclizumab
TECFIDERA® (Dimethyl Fumarate) Data Reinforce Strong, Sustained Efficacy for Newly-Diagnosed MS Patients
Daytime sleepiness versus fatigue in patients with multiple sclerosis: A systematic review on the Epworth sleepiness scale as an assessment tool.
Sex hormones and multiple sclerosis: another informative failure.
Antibodies to Epstein-Barr virus and MRI disease activity in multiple sclerosis.
You-Gui pills promote nerve regeneration by regulating netrin1, DCC and Rho family GTPases RhoA, Racl, Cdc42 in C57BL/6 mice with experimental autoimmune encephalomyelitis.
Dimethylfumarate induces apoptosis in human mast cells.
Association of common mitochondrial DNA variants with multiple sclerosis and systemic lupus erythematosus.

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