Multiple Sclerosis Discovery Forum

Inspiring Connections

Utility Navigation

User Top Menu

Drug Development

PML Death Associated With Tecfidera; FDA Issues Warning

Tecfidera product shot
Following on the heels of a confirmed case of the rare brain infection progressive multifocal leukoencephalopathy in an MS patient taking dimethyl fumarate, the FDA has just released a warning about the potential for infections in more people
Earlier this month a patient taking dimethyl fumarate died of pneumonia after developing...
Drug Development

MS Research Roundup: October 3, 2014

Research Roundup logo
Stem Cells Pass Safety Trials; Generic Similar to Copaxone; Epigenetic Differences in Monocytes and Macrophages; One Brain, Many Genomes
Items of interest to multiple sclerosis researchers from around the Web...
Clinical Research, Drug Development, Laboratory Research, Methods

Phase 2 Trial Suggests RPC1063 Is as Effective as—and Safer Than—Fingolimod

RPC1063, an experimental oral immunomodulator, is looking promising as it progresses through clinical testing. At the ACTRIMS-ECTRIMS meeting in September, Amit Bar-Or presented results of the phase 2 trial suggesting the drug is as effective as and safer than its counterpart, fingolimod.
RPC1063 may open the door to more convenient treatment options for relapsing-remitting MS, if...
Clinical Research, Drug Development

The Paradox of Daclizumab

Dr. Bibiana Bielekova
Phase 3 results show that daclizumab reduces disease activity in relapsing-remitting multiple sclerosis by half compared with interferon, as measured by brain imaging, with skin and other side effects. The drug works in surprising ways that are revealing new details about the pathogenesis of MS.
Three might be the lucky number for daclizumab, an investigational drug for relapsing-remitting multiple sclerosis with...
Clinical Research, Drug Development, Laboratory Research, Meetings


The meeting's final day featured late breakers, the closing lecture, and two masterful summaries of research highlights
Last day of #ACTRIMS #ECTRIMS 2day! L8 breaking news & closing plenary-awards...
Clinical Research, Drug Development, Laboratory Research, Meetings, Methods, People


Subscribe to RSS - Drug Development