Clinical Research

Glatiramer Acetate and the Interferon Betas Are Clinically Similar

Following on the heels of a Cochrane meta-analysis earlier in 2014, a new study finds that MS patients followed over 10 years have similar annualized relapse rates whether they take glatiramer acetate or one of the interferon betas

No matter how you slice it, glatiramer acetate and the interferon betas appear to be...

Clinical Research

MS Research Roundup: January 18, 2015

Experimental Remyelination Antibody Results; This Is Your Brain on Diapers; Neuroscience With a Conscience

Items of interest to multiple sclerosis researchers from around the Web...

Clinical Research, Drug Development, Laboratory Research

Corpus Callosum Cross-Section Correlated With Cognitive Decline

A new longitudinal study of people with MS found that the cross-sectional area of the midsagittal corpus callosum was highly associated with cognitive decline and moderately associated with physical disability over a 17-year period

A 17-year longitudinal study published online ahead of print in the Multiple Sclerosis Journal found that...

Clinical Research, Methods

Study Probes “No Evidence of Disease Activity” in MS Patients

“No evidence of disease activity,” or NEDA, means no clinical or MRI disease activity. As a treatment goal, the first study of NEDA in a “real-world” patient cohort shows plenty of room for improvement and a glimmer of hope.

Multiple sclerosis may as yet have no cure, but that’s not stopping a push to...

Clinical Research, Drug Development, Methods

Stem Cell Transplants Risky But Effective

Initial results from the HALT-MS trial suggest that autologous hematopoietic stem cell transplantation may be a highly effective treatment for patients with aggressive relapsing-remitting MS. However, some worry that the aggressive therapy is needlessly risky when safer alternatives are available and may be just as effective.

It appears that a complex series of genetic and environmental factors pile on top of each other over the course of...

Clinical Research

MS Research Roundup: January 12, 2015

Pain Comes Before Myelin Loss; HPV Vaccine Not Linked to MS; Retroviruses Common in Genomes & Activate B Cells; Posthumous Plea for Right-to-Die Reform; Oscar Wilde’s Wife May Have Had MS

Items of interest to multiple sclerosis researchers from around the Web...

Clinical Research, People

MS Research Roundup: December 21, 2014

Neurology Group Calls for Cannabis Regulation Changes; Videos and Podcasts of MS Research and Care; Alan Alda & the MSDF Manifesto

Items of interest to multiple sclerosis researchers from around the Web...

Clinical Research, Drug Development

Brain Atrophy, Early Antibody Spread in Pediatric MS

A pair of studies in a Canadian multiple sclerosis cohort finds more evidence of early neurodegenerative biology and a potentially diagnostic autoimmune antibody increase in children with MS

For most people, the first symptoms of multiple sclerosis begin in adulthood, possibly after...

Clinical Research

Azathioprine: Old Drug, New Data

Azathioprine may be as effective as interferon β in relapsing-remitting multiple sclerosis, a noninferiority trial suggests

Call it That ’80s Drug. Azathioprine (Immuran and others), a generic immunosuppressant, has been used...

Clinical Research, Drug Development, Methods

MS Research Roundup: December 12, 2014

The MS Blockbuster That Got Away; Playing Hardball With High-Priced Drugs; The Story of Gluten Intolerance

Items of interest to multiple sclerosis researchers from around the Web...

Clinical Research, Drug Development

Multiple Sclerosis Discovery Forum

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Glatiramer Acetate and the Interferon Betas Are Clinically Similar

MS Research Roundup: January 18, 2015

Corpus Callosum Cross-Section Correlated With Cognitive Decline

Study Probes “No Evidence of Disease Activity” in MS Patients

Stem Cell Transplants Risky But Effective

MS Research Roundup: January 12, 2015

MS Research Roundup: December 21, 2014

Brain Atrophy, Early Antibody Spread in Pediatric MS

Azathioprine: Old Drug, New Data

MS Research Roundup: December 12, 2014

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