Webinar: Solutions for Genome Editing: TALEN, CRISPR, & Safe Harbor Integration
17 Dec 2014
Time: 9:30 AM - 10:30 AM EDT
(3:30 PM - 4:30PM CET)
Ed Davis, Ph.D.
Senior Application Scientist
The ability to make specific changes at targeted genomic sites in complex organisms is of fundamental importance in biology and medicine. Over the past decade, researchers have developed chimeric DNA binding proteins complexed with nucleases to stimulate double strand breaks at defined genomic loci, allowing the ability to insert, delete, and replace genetic information at will. These tools can also be used without nucleases to induce or repress gene transcription.
While zinc finger nucleases (ZFNs) stimulated tremendous development in the field, they suffer from significant limitations in design capacity and specificity. Recently, bacterial DNA binding proteins, the Transcription Activator Like (TAL) and the Clustered, Regularly Interspersed, Short Palindromic Repeats (CRISPR) systems have gained favor as genome editing tools.
In this 45 minute webinar, we discuss the advantages and disadvantages of each system, and provide information on GeneCopoeia's powerful suite of genome editing products and services.