Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor. Oo M L, Thangada S, Wu M-T, Liu CH, Macdonald TL, Lynch KR, Lin C-Y, Hla T J Biol Chem. 2007 Mar 23; 282(12):9082-9. Epub 2007 Jan 21. PMID: 17237497. Abstract CommentRecommendBookmarkWatch