FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation. Choi J W, Gardell SE, Herr DR, Rivera R, Lee C-W, Noguchi K, Teo S T, Yung YC, Lu M, Kennedy G, et al. Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2):751-6. Epub 2010 Dec 21. PMID: 21177428. Abstract CommentRecommendBookmarkWatch