Icariin exerts estrogen-like activity in ameliorating EAE via mediating estrogen receptor β, modulating HPA function and glucocorticoid receptor expression.

Wei Z, Wang M, Hong M, Diao S, Liu A, Huang Y, Yu Q, Peng Z

Am J Transl Res. 2016; 8(4):1910-8. Epub 2016 Apr 15. PMID: 27186315. Abstract