Multiple Sclerosis Discovery Forum

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Biogen Idec and Genentech announce restructuring of anti-CD20 collaboration agreement
Structure of the LINGO-1-anti-LINGO-1 Li81 antibody complex provides insights into the biology of LINGO-1 and the mechanism of action of the antibody therapy.
Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells.
Estriol preserves synaptic transmission in the hippocampus during autoimmune demyelinating disease.
Equivalent Gene Expression Profiles between Glatopa™ and Copaxone®.
Suppression of CD4+ T cell activation by a novel inhibitor of Src family kinases.
Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice.
Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis.
Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects.
Japanese macaque encephalomyelitis: a spontaneous multiple sclerosis-like disease in a nonhuman primate.
Autoimmune tolerance eliminates relapses but fails to halt progression in a model of multiple sclerosis.
Direct immunomodulatory influence of IFN-β on human astrocytoma cells.
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG)
Gender-specific expression of beta1 integrin of VLA-4 in myelin basic protein-primed T cells: implications for gender bias in multiple sclerosis.
An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation.
Early magnetic resonance imaging predictors of clinical progression after 48 months in clinically isolated syndrome patients treated with intramuscular interferon β-1a.
FP187 – Oral Immunomodulatory Dimethyl Fumarate (DMF)
Mycophenolate mofetil for relapsing-remitting multiple sclerosis.
Paternal therapy with disease modifying drugs in multiple sclerosis and pregnancy outcomes: a prospective observational multicentric study.
No evidence of disease activity: indirect comparisons of oral therapies for the treatment of relapsing-remitting multiple sclerosis.
The pathology of acute disseminated encephalomyelitis produced experimentally in the rhesus monkey and its resemblance to human demyelinating disease.
Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex.
The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system.
Zist Daru, ZIFERON

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