Editors' Pick

Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation.

di Penta A, Moreno B, Reix S, Fernandez-Diez B, Villanueva M, Errea O, Escala N, Vandenbroeck K, Comella JX, Villoslada P

PLoS One. 2013; 8(2):e54722. Epub 2013 Feb 19. PMID: 23431360. Abstract

Papers: 11 Feb 2013 - 18 Feb 2013

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Editors' Pick

A genome-wide association study of brain lesion distribution in multiple sclerosis.

Gourraud P-A, Sdika M, Khankhanian P, Henry RG, Beheshtian A, Matthews PM, Hauser SL, Oksenberg JR, Pelletier D, Baranzini SE

Brain. 2013 Feb 13. PMID: 23412934. Abstract

A GWAS Gets Into Shape

Researchers connect gene variants to structure of brain lesions

Researchers have combed through our DNA to pinpoint gene versions that make some people more...

Clinical Research, Methods

Editors' Pick

Cytotoxic NKG2C+ CD4 T Cells Target Oligodendrocytes in Multiple Sclerosis.

Zaguia F, Saikali P, Ludwin S, Newcombe J, Beauseigle D, McCrea E, Duquette P, Prat A, Antel JP, Arbour N

J Immunol. 2013 Feb 8. Epub 1969 Dec 31. PMID: 23396942. Abstract

Papers: 4 Feb 2013 - 11 Feb 2013

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Resisting Arrest

Regulatory T cells outmatched in active disease

If immunology had its own comic book series, a recurring MS story line would pit...

Laboratory Research

Papers: 28 Jan 2013 - 4 Feb 2013

Check out this week's papers from PubMed. If you are a member, please log in to recommend and comment on papers. If you are not a member, please register today and join the conversation.

Editors' Pick

Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride.

Arun T, Tomassini V, Sbardella E, de Ruiter MB, Matthews L, Leite M I, Gelineau-Morel R, Cavey A, Vergo S, Craner M, et al.

Brain. 2013 Jan; 136(Pt 1):106-15. Epub 1969 Dec 31. PMID: 23365093. Abstract

Editors' Pick

Fibronectin aggregation in multiple sclerosis lesions impairs remyelination.

Stoffels JMJ, de Jonge JC, Stancic M, Nomden A, van Strien ME, Ma D, Sisková Z, Maier O, ffrench-Constant C, Franklin RJM, et al.

Brain. 2013 Jan; 136(Pt 1):116-31. Epub 1969 Dec 31. PMID: 23365094. Abstract

Multiple Sclerosis Discovery Forum

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