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MS Trial Alert: Researchers Nationwide Recruiting Children and Adolescents with MS for a Global Study of Gilenya

Summary: Investigators across the U.S. and in other countries are recruiting 190 children and adolescents with MS (ages 10-17) for a clinical trial comparing the effectiveness of oral fingolimod (Gilenya®, Novartis Pharmaceuticals AG) with interferon beta-1a (Avonex®, Biogen Idec) injected into the muscle. The study is funded by Novartis. The U.S.

Time to Rethink CIS Criteria

Jagan Avasarala
It’s time to rethink the diagnostic criteria for clinically isolated syndrome. CIS is defined as...
About 20% of patients do not meet the diagnostic criteria of clinically isolated syndrome (CIS) based on radiological and clinical evidence. Patients who do not fit the CIS diagnostic criteria may yet have oligoclonal bands distinct to CSF, increased IgG synthesis rate and IgG index and must be treated as if they carried a diagnosis of CIS.
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