Multiple Sclerosis Discovery Forum

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Flupirtine shows functional NMDA receptor antagonism by enhancing Mg2+ block via activation of voltage independent potassium channels. Rapid communication.
Insight into the mechanism of laquinimod action.
β-Amyloid: Enemy or Remedy?
Regulation of prefrontal cortex myelination by the microbiota.
Masitinib is being investigated in the treatment of amyotrophic lateral sclerosis (ALS)
Study of teriflunomide in reducing the frequency of relapses and accumulation of disability in patients with multiple sclerosis (TEMSO)
Weekly vaccination with Copaxone (glatiramer acetate) as a potential therapy for dry age-related macular degeneration.
Clinical utility of testing AQP4-IgG in CSF: Guidance for physicians.
Glatiramer acetate in primary progressive multiple sclerosis: results of a multinational, multicenter, double-blind, placebo-controlled trial.
Interferon-beta stabilizes barrier characteristics of the blood-brain barrier in four different species in vitro.
NICE recommends new treatment option for multiple sclerosis (Dimethyl fumarate)
Teriflunomide for multiple sclerosis.
Increased incidence of central nervous system hemorrhages in patients with secondary acute promyelocytic leukemia after treatment of multiple sclerosis with mitoxantrone?
Molecular characterization of a peripheral receptor for cannabinoids.
Genzyme reports positive top-line results of TOWER, a pivotal phase III trial for AUBAGIO(TM*) (teriflunomide) in relapsing multiple sclerosis
Genzyme Announces EMA Accepts Oral Teriflunomide Marketing Application for Treatment of Multiple Sclerosis
45th European Brain and Behaviour Society Meeting
Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis.
Adaptive autoimmunity and Foxp3-based immunoregulation in zebrafish.
Reliable volumetry of the cervical spinal cord in MS patient follow-up data with cord image analyzer (Cordial).
Long-term use of glatiramer acetate by 11 pregnant women with multiple sclerosis: a retrospective, multicentre case series.
Estriol Treatment in Multiple Sclerosis: Effect on Cognition
Fingolimod versus intramuscular interferon in patient subgroups from TRANSFORMS.
Pharmacokinetics, pharmacodynamics, and safety of peginterferon beta-1a in subjects with normal or impaired renal function.
IFNbeta lowers MMP-9/TIMP-1 ratio, which predicts new enhancing lesions in patients with SPMS.

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