Multiple Sclerosis Discovery Forum

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Estriol preserves synaptic transmission in the hippocampus during autoimmune demyelinating disease.
An RNA profile identifies two subsets of multiple sclerosis patients differing in disease activity.
Biogen Idec and Genentech announce restructuring of anti-CD20 collaboration agreement
Comparative pharmacogenetics of multiple sclerosis: IFN-β versus glatiramer acetate.
Episode 44 with Dr. Monika Bradl on an animal model for neuromyelitis optica (NMO)
Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells.
Equivalent Gene Expression Profiles between Glatopa™ and Copaxone®.
INF-β1b therapy modulates L-arginine and nitric oxide metabolism in patients with relapse remittent multiple sclerosis.
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Mycophenolic acid inhibits IL-2-dependent T cell proliferation, but not IL-2-dependent survival and sensitization to apoptosis.
Autoimmune tolerance eliminates relapses but fails to halt progression in a model of multiple sclerosis.
Heartbleed Bug
Phase III study: Ocrelizumab significantly reduces disease activity in PPMS patients
National MS Society: Postdoctoral Fellowships
Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects.
20th Annual Rehabilitation In Multiple Sclerosis (RIMS) Conference
American Society for Neurochemistry 47th Annual Meeting
Structure of the LINGO-1-anti-LINGO-1 Li81 antibody complex provides insights into the biology of LINGO-1 and the mechanism of action of the antibody therapy.
Episode 61 with Dr. Yanming Wang on molecular imaging of the myelin sheathing of axons
Suppression of CD4+ T cell activation by a novel inhibitor of Src family kinases.
Effect of glatiramer acetate on conversion to clinically definite multiple sclerosis in patients with clinically isolated syndrome (PreCISe study): a randomised, double-blind, placebo-controlled trial.
An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation.
Invitation to Share Your Thoughts on a New MS Research Resource
Direct immunomodulatory influence of IFN-β on human astrocytoma cells.
Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex.

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