Blood Serum From Relapsing MS Patients May Damage the Blood-Brain Barrier
Serum from relapsing MS patients reduced cultured brain cells’ expression of tight junction molecules and increased the expression of cell adhesion molecules that promote cytokine-activated leukocyte migration. If these serum factors are also present in plasma or whole blood, the research raises questions about the safety of blood donations from people with MS.
Serum from relapsing MS patients reduced cultured brain cells’ expression of tight junction molecules and increased the expression of cell adhesion molecules that promote cytokine-activated leukocyte migration. If these serum factors are also present in plasma or whole blood, the research raises questions about the safety of blood donations from people with MS.
When cultured cells of the blood-brain barrier are treated with serum from MS patients...
Laboratory Research
