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New Findings | 27 Sep 2013

The Many Faces of B Cells

Experimental therapy prompts a closer look at immune cells

Carol Cruzan Morton

Five years ago, just as the global economy plummeted, interest in B cells spiked upward among...

Laboratory Research

New Findings | 23 Sep 2013

Oral Laquinimod May Reduce Destructive Pathology in RRMS

Laquinimod appears to reduce brain MRI findings of inflammatory destruction in relapsing-remitting multiple sclerosis

Laurie Barclay, M.D.

Treatment with oral laquinimod may reduce MRI evidence of destructive brain pathology in...

Clinical Research, Drug Development

New Findings | 17 Sep 2013

Single Calcitriol Dose Beats Back EAE in Mice

Vitamin D zaps inflammatory T cells in the CNS and leads to sustained remission

Jessica Shugart, Ph.D.

Just a single dose of calcitriol—the active form of vitamin D—reversed...

Laboratory Research

New Findings | 16 Sep 2013

Corticosteroids Ineffective for Many With Relapsing MS

This study of nearly 4500 patients with MS concluded that although most felt corticosteroids helped them during relapses, a sizable percentage perceived no discernible effect or even harm

Steven Fox

Even though corticosteroid therapy, along with other therapies, is a cornerstone of managing relapsing-remitting multiple sclerosis...

Clinical Research

New Findings | 12 Sep 2013

Stem Cells Enhanced to Generate Myelin-Producing Cells

A new technology enhances stem cells to generate myelin-producing cells. This may allow regenerative therapy in MS and other brain diseases.

Laurie Barclay, M.D.

A new method of generating embryonic stem cells that can ultimately produce myelin may allow...

Laboratory Research

New Findings | 11 Sep 2013

First-Attack Multiple Sclerosis Targets Gray Matter

A new technique has identified changes in gray matter-related proteins in CSF that distinguished first-attack CIS from established relapsing-remitting MS and from controls

Daniel M. Keller, Ph.D.

Using a highly sensitive and precise proteomics technique, researchers have discovered...

Clinical Research, Laboratory Research

New Findings | 9 Sep 2013

Type 1 Diabetes Linked to Higher MS Risk Among Youth

Risk of comorbid MS was higher in youth with type 1 DM, but environmental factors may affect risk

Laurie Barclay, M.D.

Risk of comorbid multiple sclerosis was higher in children and adolescents with type 1 diabetes, but...

Clinical Research

New Findings | 9 Sep 2013

Sexual Dysfunction Fuels Mental Problems in MS Patients

Sexual dysfunction appears to have a significant impact on mental health in people with MS

Steven Fox

In people with multiple sclerosis, sexual dysfunction has a much more detrimental effect on...

Clinical Research

New Findings | 4 Sep 2013

Video Game Revs Up Brain Power

Targeted training boosts general working memory, attention

Carol Cruzan Morton

Even healthy aging brains can have a tough time concentrating in the middle of distractions and...

Clinical Research

New Findings | 3 Sep 2013

Sleep Boosts Remyelinating Glial Cells

Oligodendrocyte precursor cells proliferate during sleep in mice. Could increasing the pool of this critical cell type tip the balance toward remyelination?

Stephani Sutherland

Multiple sclerosis robs neurons of myelin, but replenishment of lost myelin could be improved...

Laboratory Research