Multiple Sclerosis Discovery Forum

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New Findings | 5 Aug 2013

More Signal Abnormalities Seen in Relatives of MS Patients

Relatives of people with MS have more white matter signal abnormalities than matched controls.

Steven Fox

Healthy relatives of people with multiple sclerosis demonstrate a higher frequency of white matter signal abnormalities and...

Clinical Research

New Findings | 5 Aug 2013

Anti-EBV Serology, HLA-DR Risk Profiles May Help Identify MS

Adding anti-EBV levels to HLA-DR risk profiles may significantly help discriminate MS cases from controls

Laurie Barclay, M.D.

Epstein-Barr virus serology and human leukocyte antigen-DR alleles may significantly help discriminate...

Clinical Research

New Findings | 29 Jul 2013

Venocentric Lesions on MRI: An Early Marker of MS?

A review article suggests that venocentric lesions seen on MRI may be an early marker of MS

Steven Fox

Venocentric lesions seen on magnetic resonance imaging may be associated with future risk of...

Clinical Research

New Findings | 29 Jul 2013

Small Internal Jugular Veins Linked to Severe MS

Small internal jugular veins with restricted outflow, but not CCSVI per se, are linked to severe MS

Laurie Barclay, M.D.

The presence of small internal jugular veins with restricted outflow, but not chronic cerebrospinal venous insufficiency...

Clinical Research

New Findings | 26 Jul 2013

Cortical MS Lesions Linked to “Normal” White Matter Injury

Cortical MS lesion load is linked to normal-appearing white matter degeneration on 7-tesla MRI

Laurie Barclay, M.D.

Cortical lesion load is correlated with normal-appearing white matter degeneration seen with...

Clinical Research, Methods

New Findings | 22 Jul 2013

Oral Cannabinoid Dronabinol Doesn’t Modify Disease in Progressive MS

Randomized controlled trial concluded that dronabinol, an oral cannabinoid, had no effect on the course of progressive MS

Steven Fox

Administration of the oral cannabinoid dronabinol appears to have no overall effect on the course...

Clinical Research

New Findings | 22 Jul 2013

Abnormal Venous Outflow Dynamics May Not Be Implicated in MS

Imaging did not show chronic cerebrospinal venous insufficiency to be common or significant in MS patients

Laurie Barclay, M.D.

Altered venous outflow dynamics are not common or pathophysiologically significant in patients with multiple sclerosis...

Clinical Research, Methods

New Findings | 17 Jul 2013

MS-SMART Trial for Secondary Progressive MS Announced

The phase 2 trial will compare amiloride, ibudilast, and riluzole to placebo

Robert Finn

The MS Society UK today announced that a new clinical trial will begin accruing patients...

Clinical Research

New Findings | 15 Jul 2013

Transcutaneous Electrical Nerve Stimulation Shows Promise in MS

This study found that electrical nerve stimulation reduced cortical motor representation in MS

Steven Fox

Daily transcutaneous electrical nerve stimulation may decrease cortical motor representation in patients with MS...

Clinical Research

New Findings | 15 Jul 2013

NMDA Receptors May Modulate Severity of Multiple Sclerosis

Genetic analysis shows that NMDARs may affect MS severity via synaptic transmission and plasticity

Laurie Barclay, M.D.

Glutamate N-methyl-D-aspartate receptors may affect synaptic transmission and plasticity, thereby modulating...

Clinical Research